Obsessive compulsive symptoms presented during the course of chronic normal pressure hydrocephalus: a case report Normal pressure hydrocephalus (NPH) is usually presented with psychiatric symptoms. Obsessive compulsive disorder (OCD) and NPH comorbidity is rare and there are only few case reports on this topic.Our case who had chronic NPH secondary to intracranial hemorrhage presented with obsessive compulsive (OC) symptoms while he was treated at neurology inpatient clinic for epilepsy. He benefited from sertraline and quetiapine treatment. Our case is thought to be the first case in terms of comorbidity of chronic NPH and OC symptoms in Turkey.
IntroductionThe association between childhood trauma and psychotic symptoms is still not clearly understood. Findings for positive and negative symptoms are confounding. This symptomatic response may differ according to the type of childhood trauma, for example childhood abuse was associated with positive symptoms while childhood neglect was associated with negative symptoms.ObjectivesThis study examined the relationship between childhood trauma and psychotic symptoms in schizophrenic patients after controlling for the possible confounding factors, such as clinical features, depression, and sleep quality.MethodsThe childhood trauma questionnaire – short form, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia, Pittsburgh sleep quality index, and the suicidality subscale of mini-international neuropsychiatric interview were administered to 199 patients with schizophrenia. We used sequential multiple stepwise regression analyses in which positive symptoms, negative symptoms, overall psychopathology and total symptoms of schizophrenia were dependent variables.ResultsDepressive symptomatology and childhood physical abuse (CPA) significantly contributed to positive, negative, general psychopathology and global schizophrenia symptomatology. Stepwise regression analysis results are presented in Table 1.ConclusionsOur findings suggest that CPA during childhood could have an impact on psychopathology in schizophrenia.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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