Osteoid osteoma (OO) is a benign tumor that is frequently seen in young people usually in the second and third decade. Tumor localization may be in cortical or cancellous bone. [1] Radiologically, a surrounding sclerotic lesion and a structure called "nidus" are present. Clinically, night pain is typical and frequently responds well to nonsteroidal drugs. There are many treatment modalities for OO including medical treatment, percutaneous radiofrequency ablation (RFA) treatment, and open surgical procedures. [1] However, despite all these different treatment methods, recurrence of OO is a significant problem. The protocol for a successful treatment should be planned in a different way for each patient. The multidisciplinary approach is an appropriate method for the treatment of various diseases that decreases the rate of morbidity in radiologic interventions as well as in many other fields of medicine. The synergy created by multiple disciplines Objectives: This study aims to present the importance of a multidisciplinary approach to radiofrequency ablation (RFA) treatment in osteoid osteoma (OO) patients by a team of experts in their field in preventing recurrence and complications. Patients and methods: For this retrospective study, a team of two orthopedists, two interventional radiologists, and one anesthesiologist was established in January 2013 to manage the diagnosis, follow-up, and treatment process of patients with OO at Bakırköy Dr. Sadi Konuk Training and Research Hospital. A total of 27 patients (15 males, 12 females; mean age 22.9 years; range, 9 to 54 years) were treated by this team between February 2013 and September 2016. The anatomic localization included iliac crest in four patients, the femur in 12 patients, fibula in two patients, humerus in three patients, radius in one patient, tibia in three patients, talus in one patient, and metacarpal in one patient. The procedures were carried out by the same interventional radiologists, same orthopedic surgeons, and same anesthesiologist in the computed tomography (CT) unit under aseptic conditions. After appropriate anesthesia for the localization of OO, the patient was positioned on the CT bed and the localization of the lesion was confirmed with a CT scan mapping. Then, a bone penetration cannula was advanced and bone cortex was penetrated with a charged motor and Kirschner (K)-wire. When the cannula reached the nidus, it was replaced with RFA probe. Ablation of the nidus was performed for five minutes at 90°C. Results: The mean follow-up period was 46 months (range, 25 to 66 months). Patients were evaluated with visual analog scale (VAS) scores preoperatively and at postoperative 15 th day, sixth month, and first year. In the last evaluation of the study data, the patients were called by telephone and questioned whether there were any changes in their final status. The mean preoperative VAS score was 7.2. The mean postoperative VAS scores of the 15 th day, sixth month, and first year were 1.3, 0.6, and 0, respectively. In the last follow-up, the OO...