Color-shift keying (CSK) is a visible light communication (VLC) intensity modulation scheme, outlined in IEEE 802.15.7, that transmits data imperceptibly through the variation of the light color emitted by a red, green, and blue (RGB) light emitting diode (LED). Unlike other intensity modulation schemes, CSK guarantees that the intensity of the luminary will not fluctuate, thus limiting potential human health complications related to flickering light.In this work, a rigorous design framework for CSK constellations is presented. The benefits of the frame work are that it can optimize constellations while accounting for cross talk between the color communication channels formed by the colored LEDs.Unlike previous works, the method applies the study of colorimetry to optimize higher order CSK constellations such that the luminary functions with a desired operating color, allowing constellations to be designed to meet lighting industry quality metrics.
A fusion protein vaccine consisting of human papillomavirus 6 L2E7 with Alhydrogel was developed for the treatment of genital warts. Twenty-seven subjects with genital warts received 3 immunizations over 4 weeks in an open-label study. The vaccine was well-tolerated, and all subjects made serum IgG antibodies, predominantly IgG1, against L2E7. Nineteen of 25 tested persons made antigen-specific T cell proliferative responses to L2E7, and peripheral blood mononuclear cells when cultured with L2E7 in vitro produced both interferon-gamma and interleukin (IL)-5, although IL-5 predominated after the final vaccination. Five subjects completely cleared warts within 8 weeks. Subjects whose warts were not cleared by 8 weeks were offered conventional therapy. Recurrence of warts was not seen in any of the 13 persons whose warts cleared by vaccine alone or with conventional therapy. While these preliminary results of the use of this therapeutic immunogen are encouraging, proof of efficacy will require randomized double-blind trials.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.