The classical and modified equations of Kolmogorov-Johnson-Mehl-Avrami are compared with the equations of conventional Gompertz andMontijano-Bergues-Bory-Gompertz, in the frame of growth kinetics of tumors. For this, different analytical and numerical criteria are usedto demonstrate the similarity between them, in particular the distance of Hausdorff. The results show that these equations are similar fromthe mathematical point of view and the parameters of the Gompertz equation are explicitly related to those of the Avrami equation. It isconcluded that Modified Kolmogorov-Johnson-Mehl-Avrami and Montijano-Bergues-Bory-Gompertz equations can be used to describe thegrowth kinetics of unperturbed tumors.
In the province of Santiago de Cuba, Cuba, the COVID-19 epidemic has a limited progression that shows an early small-number peak of infections. Most published mathematical models fit data with high numbers of confirmed cases. In contrast, small numbers of cases make it difficult to predict the course of the epidemic. We present two known models adapted to capture the noisy dynamics of COVID-19 in the Santiago de Cuba province. Parameters of both models were estimated using the approximate-Bayesian-computation framework with dedicated error laws. One parameter of each model was updated on key dates of travel restrictions. Both models approximately predicted the infection peak and the end of the COVID-19 epidemic in Santiago de Cuba. The first model predicted 57 reported cases and 16 unreported cases. Additionally, it estimated six initially exposed persons. The second model forecasted 51 confirmed cases at the end of the epidemic. In conclusion, an opportune epidemiological investigation, along with the low number of initially exposed individuals, might partly explain the favorable evolution of the COVID-19 epidemic in Santiago de Cuba. With the available data, the simplest model predicted the epidemic evolution with greater precision, and the more complex model helped to explain the epidemic phenomenology.
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