Gagal ginjal kronis (GGK) merupakan penyakit yang bersifat kompleks dan mempengaruhi berbagai organ, termasuk kulit. Manifestasi dermatologik sangat sering ditemukan pada pasien gagal ginjal kronis, terutama pada stadium gagal ginjal terminal. Secara umum, manifestasi dermatologik pada gagal ginjal kronis dibagi menjadi dua, yaitu non-spesifik dan spesifik. Manifestasi non-spesifik meliputi xerosis, pruritus, kelainan kuku, kelainan rambut, perubahan pigmen kulit, ekimosis, purpura, kelainan mukosa, uremic frost, ginekomastia, infeksi kulit, dan manifestasi kulit yang disebabkan penggunaan obat imunosupresif. Sedangkan manifestasi spesifik meliputi acquired perforating dermatosis (APD), kalsifilaksis, penyakit bulosa, dan nephrogenic systemic fibrosis (NSF). Diagnosis dan terapi dini termasuk tindakan profilaksis dapat mengurangi morbiditas dan meningkatkan kualitas hidup pasien.
Giant Congenital Melanocytic Nevi (GCMN) is a nevus which present at birth or arise within the first few weeks of life. Incidence of GCMN is estimated at below 1:20.000 newborns. Lesion of GCMN usually appears with a black or brownish plaque and may have abnormal borders, flat or protruding surface and hypertrichosis. Giant Congenital Melanocytic Nevi (GCMN) is associated with malignant melanoma and neurocutaneous melanocytosis. A male newborn baby is reported to have a giant black hairy plaque, with irregular shape in his head since born. Patient was born naturally, full term, and normal birth weight. The mother has no medication consumption and disease history during pregnancy. In our three years follow up, there are multiple black patches with smaller size in front right and left leg, and the back of the body. The GCMN treatment consists of surgical and non-surgical procedures, psychological support, and lifelong monitoring. In this case, further examination and observation are needed.
Mycoplasma genitalium merupakan suatu mikroorganisme yang berasal dari kelas Mollicutes, tumbuh lambat, dan mampu bereplikasi secara independen. Mycoplasma genitalium telah ditetapkan sebagai salah satu organisme patogen penyebab infeksi menular seksual dalam beberapa dekade terakhir. Transmisi M. genitalium dapat secara genito-genital, ano-genital, namun jarang secara oro-genital. Infeksi M. genitalium dapat bersifat asimptomatik, namun dapat berupa uretritis akut atau kronik, servisitis, dan penyakit radang panggul. Deteksi M. genitalium dengan pewarnaan Gram dan kultur sulit dilakukan, sehingga memerlukan amplifikasi asam nukleat. Penderita infeksi M. genitalium perlu diberikan edukasi menyeluruh mengenai penyakitnya bersama dengan pasangan seksualnya, dan disarankan melakukan abstinensia hubungan seksual selama 14 hari atau hingga gejala sembuh. Terapi infeksi M. genitalium berupa antibiotik seperti makrolida, fluorokuinolon, tetrasiklin, dan pristinamisin. Tingkat resistensi antibiotik yang tinggi merupakan tantangan dalam menangani infeksi M. genitalium. Artikel ini akan merangkum mengenai infeksi M. genitalium, termasuk epidemiologi, gejala klinis, diagnosis, tata laksana, dan tantangan dalam mengobati infeksi M. genitalium, serta peranannya dalam infeksi menular seksual.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.