No abstract

Fluorinated Cu(II) acetylacetonate complexes are efficient catalysts for the reaction of a variety of vinyl thiiranes to give 2,5-dihydrothiophenes in excellent yields. Thiophene (IIf) is an intermediate for the synthesis of biotin. After oxidation and deprotection, a synthetic building block to achieve antiplatelet drug Plavix in one additional step is available from product (Xb). -(ROGERS, E.; ARAKI, H.; BATORY, L. A.; MCINNIS, C. E.; NJARDARSON*, J. T.; J.

Pre-dates formal DoD distribution statements. Treat as DoD only.