BackgroundHere we report the first case of postoperative endophthalmitis due to Candida pelliculosa after cataract surgery. We describe the clinical management of this type of candida infection in the eye.Case presentationA 57-year-old Turk man was seen at our clinic at the end of the first postoperative month after cataract surgery. He presented with eye redness, pain and decreased visual acuity. His ophthalmologic examination revealed moderate tyndall and a mild flare in the anterior chamber. Hypopyon in the capsular bag posterior to the intraocular lens was seen in the second postoperative month. Despite topical and subconjunctival bacterial endophthalmitis treatment, there was no improvement in the clinical situation. Candida pelliculosa was isolated from a sample culture obtained from the anterior chamber. Oral fluconazole could not be administered because of increased liver enzyme levels and intravenous amphotericin B could not be administered because of an allergic reaction. Intraocular lens explantation, pars plana vitrectomy and anterior chamber lavage by rupturing the posterior wall of the microabscesses were performed. Intravitreal and intracameral amphotericin B injections were given four times in addition to surgical interventions. The patient has been followed for 2 years and his best-corrected visual acuity was 0.4 at the last visit.ConclusionNearly 1 month after cataract surgery, a patient presented with eye redness and blurred vision, with corneal endothelial deposits, hypopyon in the capsular bag and microabscesses on the incision sites and corneal endothelium. Candida pelliculosa should be considered in patients showing these symptoms. Multiple intraocular amphotericin B (5 μg) administrations can be used safely even in cases with high sensitivity to systemic use. Rupturing the posterior wall of the abscesses on the corneal endothelium surgically with intraocular lens explantation and pars plana vitrectomy are recommended.

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Purpose The aim of the study is to improve the accuracy of age related macular degeneration (AMD) disease in its earlier phases with proposed Capsule Network (CapsNet) architecture trained on speckle noise reduced spectral domain optical coherence tomography (SD-OCT) images based on an optimized Bayesian non-local mean (OBNLM) filter augmentation techniques. Methods A total of 726 local SD-OCT images were collected and labelled as 159 drusen, 145 dry AMD, 156 wet AMD and 266 normal. Region of interest (ROI) was identified. Speckle noise in SD-OCT images were reduced based on OBNLM filter. The processed images were fed to proposed CapsNet architecture to clasify SD-OCT images. Accuracy rates were calculated in both public and local dataset. Results Accuracy rate of local SD-OCT image dataset classification was achieved to a value of 96.39% after performing data augmentation and speckle noise reduction with OBNLM. The performance of proposed CapsNet was also evaluated on the public Kaggle dataset under the same processing procedures and the accuracy rate was calculated as 98.07%. The sensitivity and specificity rates were 96.72% and 99.98%, respectively. Conclusions The classification success of proposed CapsNet may be improved with robust pre-processing steps like; determination of ROI and denoised SD-OCT images based on OBNLM. These impactful image preprocessing steps yielded higher accuracy rates for determining different types of AMD including its precursor lesion on the both local and public dataset with proposed CapsNet architecture.

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Sahip olduğu denizi, iklimi, tarihi ve kültürel değerleri bakımından Türkiye'nin en önemli turistik çekim merkezlerinden biri olan Antalya ilinde yerli ve yabancı turist talebi sürekli artmaktadır. Bu çalışmada, Antalya merkez ilçelerinde yaşayan yerel halkın turizmin etkilerine yönelik algılarının belirlenmesi amaçlanmıştır. Araştırmanın evrenini Antalya ili merkez ilçelerinde (Konyaaltı, Muratpaşa, Kepez, Aksu ve Döşemealtı) yaşayan yerel halk oluşturmaktadır. Bu amaçla beş ilçede toplam 464 kişiye uygulanan anketin istatistiksel analizlere uygun olduğu görülmüştür. Analizler bilgisayar ortamında ve SPSS 20.00 programı yardımıyla ve 0.05 anlamlılık düzeyinde test edilmiştir. Elde edilen verilerin analizi, frekans analizleri, Mann-Whitney U testi ve Kruskall-Wallis analizleri ile gerçekleştirilmiştir. Analiz sonuçlarına bakılarak; yerel halkın turist profiline yönelik beklentilerinin nitelikli turist gelmesi yönünde olduğu, Antalya'da kontrolsüz turizm büyümesinin çevresel sorunlara neden olduğu, turizm faaliyetlerinin halkın yaşam standartlarını artırdığı, mevcut turizm politikalarının doğal kaynakların sürdürebilirliğini destekler nitelikte olmadığı sonucu ortaya çıkmıştır.