COVID-19 illness has become a serious health issue that is harming healthcare systems around the globe. It is crucial to examine the epidemiological traits of COVID-19. The study aimed to show the demographic data and their associations with the laboratory and clinical data in COVID-19 patients. 46 COVID-19 patients and 20 normal controls were involved in this study. The subjects were submitted to routine laboratory investigations, including CBC, Random glucose level, renal function test, liver profile, CRP, Ferritin, and D dimer. The study indicated no significant difference in the demographic data between COVID-19 patients and healthy controls. Covid-19 subjects' age was positively associated with blood urea and direct bilirubin levels. Increased Covid-19 patients' age was linked to ferritin and D-dimer levels (p = 0.009 and p = 0.012). Covid-19 patients' gender correlated positively with hemoglobin levels. Age was a risk factor for the severity and clinical progression of the illness.
Purpose: To assess the relationship of factor V leiden G1691A mutation as a risk factor for repeated pregnancy loss. The focus has been on factor V leiden G1691A mutation that may predispose women to microthrombosis during the stages of embryo implantation and placentation. Methods: A total of 70 women with recurrent pregnancy loss, mean age 31.1±4.2 years, were involved in the study. As a control group, 70 women [mean age 32.2±3.3 years with at least two live-born child and no history of abortion were included. We used real-time polymerase chain reaction (PCR) to determine the frequencies of factor V leiden G1691A genotype. Results: The frequency of heterozygotes for factor V leiden G1691A was significantly higher in women with repeated pregnancy loss compared to women without abortion (p = 0.0001). Conclusion: In summary we found an association of factor V leiden G1691A mutation with recurrent pregnancy loss .We recommend for factor V leiden G1691A screening in cases with repeated pregnancy loss so they can start anticoagulant therapy more earlier.
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