No abstract

No abstract

Background: Low antioxidant system may contribute to the severity of neonatal hyperbilirubinemia. Objectives: This study was performed to clarify the relationship between serum 25-hydroxyvitamin-D (25[OH] D) and the hyperbilirubinemia in full-term neonates. Study design: This is a cross sectional case control study performed with the aim of determining whether there is an association between serum indirect bilirubin and serum vitamin D levels in newborns with jaundice at a level necessitating phototherapy. The study was carried on 60 full term newborns admitted to the Neonatal Intensive Care Unit of Minia University Hospital, from April 2017 to December 2017. They were classified into 2 groups, Group I: (cases): Newborns with postnatal ages of 3-10 days and gestational ages of 37-40 weeks, with a bilirubin level above the pre-set threshold for phototherapy as recommended by the American Academy of Pediatrics (AAP). Group II :(controls) 30 matched apparently normal healthy newborns were enrolled in the study as a control group. The study included the mothers of case group. All laboratory investigations were done in clinical pathology department, Minia University hospital. Results: Serum Vitamin D levels were significantly lower in patients than controls (p<0.01). There was a strong negative correlation between neonatal total serum bilirubin level and neonatal serum vitamin D in cases group. In addition, we observed that there was a highly statistically significant positive correlation between serum vitamin D level of neonates and their maternal serum level was present. Conclusions: Indirect hyperbilirubinemia in full-term neonates is associated with decreased serum levels of (25[OH] D)

Introduction: Lifestyle modification strategies (diet and exercise) currently form the main treatments for obesity. However, results are generally disappointing and the majority of people who attempt lifestyle modification regain any lost weight within 5 years. Aim of the Work: The aim of this study was To assess the effects of bariatric procedures (sleeve gastrectomy, mini-gastric bypass, sleeve gastrectomy with loop bipartition) on local GIT hormones, (secretin hormone, ghrelin hormone, peptide YY, glucagon-like peptide 1). Patients and Methods: Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. Results: 56 Cases, 48 females and 8 males, were collected with age ranging from 20 to 50 years old and body weight ranging from 100 to 200 Kg, and subjected to laparoscopic sleeve gastrectomy, mini gastric bypass and sleeve gastrectomy with loop bipartition. Conclusion: The effect of bariatric surgery upon glucose tolerance is likely to be related to increased production of the incretin hormone, GlP-1, which has a profound insulinotropic action, coupled to the improved insulin sensitivity resulting from weight loss.