Background The pandemic of COVID19 which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first described in China as an unexplained pneumonia transmitted by respiratory droplets. Gastrointestinal (GI) and liver injury associated with SARS-CoV-2 infection were reported as an early or sole disease manifestation, mainly outside China. The exact mechanism and incidence of GI and liver involvement are not well elucidated. Main body We conducted a PubMed search for all articles written in the English language about SARS-CoV-2 affecting the GI and liver. Following data extraction, 590 articles were selected. In addition to respiratory droplets, SARS-CoV-2 may reach the GI system through the fecal-oral route, saliva, and swallowing of nasopharyngeal fluids, while breastmilk and blood transmission were not implicated. Moreover, GI infection may act as a septic focus for viral persistence and transmission to the liver, appendix, and brain. In addition to the direct viral cytopathic effect, the mechanism of injury is multifactorial and is related to genetic and demographic variations. The most frequently reported GI symptoms are diarrhea, nausea, vomiting, abdominal pain, and bleeding. However, liver infection is generally discovered during laboratory testing or a post-mortem. Radiological imaging is the gold standard in diagnosing COVID-19 patients and contributes to understanding the mechanism of extra-thoracic involvement. Medications should be prescribed with caution, especially in chronic GI and liver patients. Conclusion GI manifestations are common in COVID-19 patients. Special care should be paid for high-risk patients, older males, and those with background liver disease.

Background: Commonly used ultrasound fetal weight estimation formulas show variable degrees of error which is more evident in fetuses with nutritional and metabolic issues; better accuracy of fetal weight estimation can be obtained by incorporation of fetal soft tissue parameters like the fetal subcutaneous tissue in the weight estimation process. The aim of this study was to assess the accuracy of fetal abdominal subcutaneous tissue thickness (FASTT) as an indicator of fetal birth weight. Results: FASTT showed a high significant statistical correlation with fetal birth weight (r = 0.94, P value = 0.00); it showed higher sensitivity for large for gestational age (LGA) than small for gestational age (SGA) (90.9% and 86.9%, respectively). The best cutoff value for the detection of LGA was ≥ 9.2 mm and ≤ 4.5 for SGA. FASTT showed lower accuracy than abdominal circumference (AC) as an indicator of LGA (92% versus 96%, respectively). Used alone, FASTT is less sensitive than Hadlock formula in both LGA and SGA (90.9% versus 94.5% in LGA and 86.9% versus 88.9% for SGA, respectively). There was no statistical correlation between FASTT and mode of delivery (r = 0.09, P value = 0.23) nor fetal gender (r = 0.15, P value = 0.11) Conclusion: FASTT is a good indicator of fetal birth weight especially LGA, yet it is less sensitive than AC in the prediction of LGA. It cannot be used as a predictor of mode of delivery and not affected by fetal gender.