Objectives: The aim of this study was to evaluate the demographic profile, refractive ,topographic and tomograghic characters of keratoconus patients in Egypt. Patients and Methods: This study was designed as a retrospective cohort clinical study. The study met the ethical criteria of the Institutional Review Board (IRB) in Faculty of Medicine Benha University with approval No. of (MS 32-12-2019). Our study included 102 eyes of 51 patient in the keratoconus group and 100 eyes of 50 patients in the control group. The study was designed as a retrospective cohort clinical study on keratoconus patients who attended at Al Ferdaws eye hospital in the period from January 2016 to December 2020. Study groups: Group 1: normal eyes as a control group. Group 2: keratoconus group (KC). Data Synthesis: The results analyzed using SPSS25, T-test, Mann-Whitney U test and Chi-square test. Findings: There was clinically significant difference between normal and KC cases regarding the cylinder, BCVA, keratometric power of anterior and posterior surface on both flat and steep meridian.also K max and km.,Q value at 6 mm., thinnest location, relative thickness map average,thickness profile map average (PPI),highest elevation front and back,corneal irregularity indices, corneal aberrometric values, BAD_ D and ARTmax. Conclusion: We found no significant associationbetween the severity of KC with age and sex. many parameters in topography and tomography were efficient in differentiating normal cases from keratoconus cases even in early disease.
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