Background: Multidetector computed tomographic (MDCT) angiography has become a key imaging investigation for assessment of the renal vasculature challenging conventional angiography. Objective: To assess the diagnostic performance and accuracy of multi-detector computed tomography angiography in evaluation of renal vascular abnormalities. Subjects and Methods: Prospective study included 95 patients (60 males and 35 females) evaluated by MDCT renal аngiоgrаphy, divided into four groups .First group are renal donors prepared for renal transplant, Second group are patients with history of suspected renal trauma or post percutaneous nephrolithetomy hematuria ,Third group are patients suspected for renovascular hypertension . Fourth group are patients with renal masses assessed for preoperative angio-embolization & surgical guidance. MDCTA findings were correlated with conventional angiography or operative findings. Results: MCT angiography results show no significant statistical deference compared with intraoperative findings in first group, as well as compared with conventional angiography regards detection of pseudoaneurysmas in traumatic & post PCNL patients (P value > 0.05) in second group. In patients with suspected renovascular hypertension there was significant difference between renal artery Doppler findings & MDCT angiography as well as conventional angiography (P value <0.05). MDCT Angiography has AUC of 0.973, Sensitivity 93.3% and Specificity 90%. Conclusion: We can conclude that, MDCT Renal angiography is an excellent imaging investigation because it is a fast and non-invasive tool that provides detailed evaluation of normal renal vascular anatomy, variants &abnormalities .