We used a gonadotrophin-releasing hormone agonist (buserelin) and human menopausal gonadotrophin (HMG) for superovulation for in-vitro fertilization (IVF) in 143 patients. The patients were prospectively allocated to two balanced groups. In one group (47 patients) human chorionic gonadotrophin (HCG) was given when the three largest follicles were greater than or equal to 17 mm in diameter, with consistent levels of plasma oestradiol (standard group). In the second group (96 patients), HCG injection was delayed by 24 h (delayed group). In the delayed group of patients, proportionately more had clinical pregnancies (52.1% versus 34.0%). These results suggest that IVF patients will benefit from delayed administration of HCG. The traditional criteria for HCG administration should be changed when buserelin is used.
should not be regarded as incorrect solely on the basis of negative punch biopsy histology. IU/l (IRP). 41 had intrauterine pregnancies (38%) and three had heterotopic pregnancies (3%). Sixty five patients had ectopic pregnancy, 63 of which were scanned, 55 (87%) by vaginal ultrasound. Two patients, one with a cornual and one with a heterotopic pregnancy were not diagnosed correctly on vaginal scanning. The remaining two heterotopic pregnancies were correctly diagnosed. The sensitivity of diagnosing ectopic pregnancy by vaginal ultrasound in pregnant patients was 96% and the specificity was 100%. The positive predictive value was 100% and the negative predictive value was 92%.
P. G. Carter V. Grant-HarrisOur results confirm the findings by Cacciatore ADONIS 0306545691000585 et al. that when available, vaginal scanning is the most informative investigation in patients with suspected ectopic pregnancy.
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