In recent years, increasing attention has been paid to the effects of Type 1 Diabetes (T1D) on cognitive functions. T1D onset usually occurs during childhood, so it is possible that the brain could be affected during neurodevelopment. We selected young patients of normal intelligence with T1D onset during neurodevelopment, no complications from diabetes, and adequate glycemic control. The purpose of this study was to compare the neural BOLD activation pattern in a group of patients with T1D versus healthy control subjects while performing a visuospatial working memory task. Sixteen patients and 16 matched healthy control subjects participated. There was no significant statistical difference in behavioral performance between the groups, but, in accordance with our hypothesis, results showed distinct brain activation patterns. Control subjects presented the expected activations related to the task, whereas the patients had greater activation in the prefrontal inferior cortex, basal ganglia, posterior cerebellum, and substantia nigra. These different patterns could be due to compensation mechanisms that allow them to maintain a behavioral performance similar to that of control subjects.
Este trabajo tiene como objetivo establecer las propiedades psicométricas de la escala de gaudibilidad en una población mexicana del centro de México. El concepto de gaudibilidad ha sido definido como el conjunto de moduladores (habilidades, creencias y estilo de vida) que regulan el disfrute que experimentan las personas (Padrós y Fernández-Castro, 2008). Aplicamos la escala (de 23 ítems) a tres muestras (N = 445, 357 y 273). Nuestros resultados sugieren que la escala tiene una estructura interna de un factor, elevada consistencia interna, y alta confiabilidad test-retest. También evaluamos las posibles relaciones entre gaudibilidad y bienestar psicológico, satisfacción con la vida, depresión clínica niveles de afecto positivo y negativo. Los datos empíricos indican que la escala de gaudibilidad presenta una validez y confiabilidad satisfactorias. Dichos resultados apoyan la propuesta de que la gaudibilidad es un constructo útil para la investigación en psicología.
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