Introduction: Breast cancer a threat to global health that is already a priority nursing care for people with this condition is essential, accompaniment in the perioperative and recovery at home supports the reduction of complications and adaptation their situation, being the aggressive surgical procedure mastectomy, accompanied by other traumatic, requiring appropriate coping strategies. Objective: To design a program of nursing care that promotes coping strategies favoring adaptation and reduced complications. Materials and Methods: We performed preliminary study identifying prevalence of nursing diagnoses in women with mastectomies, are reviewed and discussed care plans published in national and international literature, we identify the modes of adaptation affected by the diagnoses presented, concluding with the proposed home care supported by type of adjustment problems and taxonomy for nursing. Results: Age prevailing 20 to 45 years and 45 to 60, 76% married, 81% no impediment to home care, the prevalence of nursing diagnoses in two health institutions is similar varying frequencies, commonly identified diagnoses are listed in the care plans published alteration are distinguished in the four modes of adaptation, based on the information conforms algorithm performance as a proposed program of home care. Discussions and Conclusions: The development of exploratory and logical deductive analysis, an approach allows the phenomenon of study, and supports the implementation of multidisciplinary care programs.