Introduction:The central retina is responsible for several visual functions and continues to develop postnatally. In albinism, which is a genetic disorder characterized by impaired melanin biosynthesis, the development of the central retina is prematurely arrested and results in foveal hypoplasia. Retinal thickness measurements can be determined noninvasively using optical coherence tomography systems. This article reports on the retinal thickness measurements of individuals with albinism in South Africa to aid in the assessment and management of affected individuals. Methods: The study used a comparative research design and included 60 individuals (30 albinism and 30 controls) aged from 10 to 30 years who accessed the eye clinic at a tertiary institution in KwaZulu-Natal, South Africa. The Optovue iVue100 optical coherence tomographer was used to measure retinal thickness in the nine Early Treatment Diabetic Retinopathy Study (ETDRS) sectors including the central foveal, parafoveal and perifoveal regions. Study data were analysed using descriptive and inferential statistics.Results: The mean central foveal thickness was significantly higher in individuals with albinism compared with controls (289 µm versus 239 µm, p < 0.001). In contrast, control participants showed thicker retinal thickness measurements in the other ETDRS sectors (p < 0.001). The nasal and temporal quadrants were thickest and thinnest, respectively, in the parafoveal and perifoveal regions for the albinism and control groups. Conclusion: Individuals with albinism, aged from 10 to 30 years, have higher central foveal thickness but thinner retinal thickness measurements in the parafoveal and perifoveal regions. Optometric personnel should consider these measurements when assessing individuals with albinism with foveal retinal diseases.
Power generation is becoming an increasing problem in South Africa. South Africa produces approximately 90% of its electricity from coal-fired power stations and only 5% from hydroelectric power stations and pumped storage. Durban has a very steep topography, which results in high pressure in certain parts of the water distribution network (WDN). Leakage is costly and contributes to a large extent to non-revenue water (NRW) in the network. Pressure reducing valves (PRVs) are used in WDNs to control the pressure in the pipework to reduce leakage. This excess pressure can be used to generate electricity by a pump acting as a turbine (PAT). The electricity generated is a function of the flow rate and the pressure reduction through the PAT. The hydraulic modelling software EPANET 2.2 is used for the analysis of the Cornubia Integrated Human Settlement Development Phase 2A WDN in Durban. EPANET is used to determine the strategic placement of PATs in the WDN and their setting and configuration to extract the most energy and reduce pressure in the system. A configuration of five PATs of different sizes extracts a total power output of 166.31 kW and reduces leakage in the WDN by 45.59 kL per month, which is an 18.16% reduction in leakage.
Peer review declarationThe publisher (AOSIS) endorses the South African 'National Scholarly Book Publishers Forum Best Practice for Peer Review of Scholarly Books'. The manuscript underwent an evaluation to compare the level of originality with other published works and was subjected to rigorous two-step peer review before publication, with the identities of the reviewers not revealed to the editor(s) or author(s). The reviewers were independent of the publisher, editor(s), and author(s). The publisher shared feedback on the similarity report and the reviewers' inputs with the manuscript's editor(s) or author(s) to improve the manuscript. Where the reviewers recommended revision and improvements, the editor(s) or author(s) responded adequately to such recommendations. The reviewers commented positively on the scholarly merits of the manuscript and recommended that the book be published.
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