We previously reported that a severe acquired immune deficiency syndrome-like disease develops in transgenic (Tg) mice expressing the human immunodeficiency virus-1 in its natural target cells: immature and mature CD4 ؉ T cells and cells of the macrophage/ dendritic lineage. Here, we show that these mice also develop cardiac disease, characterized most prominently by a focal myocytolysis, occasionally by myocarditis and by deposition of endogenous immunoglobulin on cardiomyocytes. Microfil perfusion demonstrated widespread coronary arteriospasm and echocardiographic analysis revealed depressed cardiac function in Tg mice. A higher (but still modest) level of cardiomyocyte apoptosis was detected in Tg as compared to non-Tg hearts. Tg expression was detected in some of the infiltrating mononuclear cells, but not in cardiomyocytes or in cells of the heart vessels, suggesting a human immunodeficiency virus-1-induced disease process mediated by cells of the immune system. The similarity of the heart disease observed in these Tg mice to that observed in acquired immune deficiency syndrome patients suggests a common pathogenesis.
A Doubly Fed Induction Generator Wind Turbine (DFIG-WT) with FACTS capabilities is presented. It is suggested to make use of the grid-side converter as a shunt active filter in order to support the grid with power factor correction as well as harmonic compensation. A vector control scheme is used to control the grid-side converter with a priority level feature to split extra room for compensation. It allows the grid-side converter to be remote-controlled and provide power quality support at a specific point away from the wind turbines plant. No harmonics are injected into the generator and the system is fully operational even at zero output power from the DFIG-WT. Simulation results illustrate good performance of the proposed system.Index Terms--Wind power generation, active filter, doublyfed induction generator, power quality, grid-side converter control.
A Doubly Fed Induction Generator Wind Turbine (DFIG-WT) under unbalanced load condition is presented. It is demonstrated that the grid-side converter can supports the grid under unbalanced load conditions as well as provide power factor correction without disturbing the DFIG-WT. The controller is based on symmetrical components and a vector control scheme. With the grid-side converter, power compensation support can be done at a specific point away from the wind turbine plant. The system is fully operational at zero output power from the DFIG-WT and independent of the rotor-side control strategy. Simulation results illustrate good performance of the proposed system.
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