This study aimed to determine the effect of pastoral counseling on thepsycho-spiritual well-being of the seminarians. It utilized the pretestposttestcontrol group experimental design. Thirty-two seminariansparticipated in the study. The seminarians were randomly assigned tothe experimental group and the control group, with 14 participants and18 participants, respectively. The saliva pH strips and the PsychologicalGeneral Well-Being Index (PGWBI) were used to measure thepsychological well-being, while the Spiritual Well-Being Questionnaire(SWBQ) was used to measure spiritual well-being. The results of thestudy revealed that there was a significant difference in psycho-spiritualwell-being between the experimental group and the control group afterthe strategic pastoral counseling. The findings suggest implications instrategic pastoral counseling as an effective program for the improvementand sustainability of the psycho-spiritual well-being of the seminarians.