The crystal structure of the tetrameric alpha2beta2 acetyl-coenzyme A synthase/carbon monoxide dehydrogenase from Moorella thermoacetica has been solved at 1.9 A resolution. Surprisingly, the two alpha subunits display different (open and closed) conformations. Furthermore, X-ray data collected from crystals near the absorption edges of several metal ions indicate that the closed form contains one Zn and one Ni at its active site metal cluster (A-cluster) in the alpha subunit, whereas the open form has two Ni ions at the corresponding positions. Alternative metal contents at the active site have been observed in a recent structure of the same protein in which A-clusters contained one Cu and one Ni, and in reconstitution studies of a recombinant apo form of a related acetyl-CoA synthase. On the basis of our observations along with previously reported data, we postulate that only the A-clusters containing two Ni ions are catalytically active.
We elucidate the role of zonal flows in transient phenomena observed during L-H transition by studying a simple L-H transition model which contains the evolution of zonal flows, mean ExB flows, and the ion pressure gradient. Zonal flows are shown to trigger the L-H transition and cause time-transient behavior through the self-regulation of turbulence before a mean shearing, due to a steep pressure profile, secures a quiescent H mode. Surprisingly, this self-regulation lowers the power threshold for the ultimate transition to a quiescent H-mode state.
We study the generation and evolution of density perturbations and peculiar
velocities due to primordial magnetic fields. We assume that a random magnetic
field was present before recombination and follow the field's effect on the
baryon fluid starting at recombination. We find that magnetic fields generate
growing density perturbations on length scales larger than the magnetic Jeans
length, $\lambda_B$, and damped oscillations for scales smaller than
$\lambda_B$. For small wavenumbers $k$ (large length scales), we find the
magnetic field-induced density power spectrum generally scales as $k^4$. We
derive the magnetic Jeans length explicitly by including the back--reaction of
the velocity field onto the magnetic field by decomposing the magnetic field
into a force-free background field and perturbations about it. Depending on the
strength of the magnetic field and the ultraviolet cutoff of its spectrum,
structure can be generated on small or intermediate scales early in the history
of the universe. For a present {\it rms} magnetic field of $10^{-10}$ G on
intergalactic scales, we find that perturbations on galactic scales could have
gone non--linear at $z \simeq 6$. Finally, we discuss how primordial magnetic
fields affect scenarios of structure formation with non--baryonic dark matter.Comment: Final version to appear ApJ, August 1996. Significant changes in the
formal approach but similar conclusions. 47 pages, plain TeX, 3 figures
available from olinto@fnalv.fnal.go
The described angiographic classification provides considerable information concerning the characteristics of AVMs in the body and extremities, the optimal therapeutic approach, and the likely therapeutic outcome.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.