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Objective: Meta-analysis was conducted to examine effects of OT interventions based on sensory stimulation, environmental modification and functional task activity on the behavioral problems and depression of individual with dementia. Search strategy: An extensive search in database such as MEDLINE, CINAHL, ProQuest Medical Library, and Cochrane and OT related 11 journals was performed. Selection criteria: Potential studies were identified through the keywords: dementia or Alzheimer, randomized controlled trials and occupational therapy or occupational therapist or ADL or sensory stimulation or Snoezelen or environmental modification or education for caregivers. Data collection and analysis: Two reviewers independently identified studies, extracted data, assessed methodological quality of the studies. Effect size was estimated using standardized mean difference with 95% confidence intervals. Significant heterogeneity and publication bias were investigated. Main results: Nine studies including 751 people were selected. Sensory stimulation was effective intervention in improving behavioral problems (0.32; 95% CI, 0.04 to 0.59). Conclusion: This review identified that OT intervention based on sensory stimulation was effective intervention to improve behavioral problems. However, the number of studies included in this review is limited. More research is needed to enable evidence-based OT for dementia patients.

Compared with conventional MP-RAGE, the proposed CE BB-ssTSE imaging, which enhances tumors while selectively suppressing blood vessels, leads to significantly better detection of small metastatic brain tumors <5 mm.

Experienced readers have a better ability to detect esophageal varices on liver MDCT, but had no higher performance to evaluate high-risk esophageal varices. As the accuracy of detecting high-risk esophageal varices with clinical relevance on liver MDCT is excellent, even by endoscopists, the evaluation of esophageal varices from a recent liver MDCT may be useful to avoid the use of low-yield endoscopy.

Background There may be discordance between tumor size determined by magnetic resonance imaging (MRI) and that observed during pathologic analyses. Purpose To evaluate MRI-pathology concordance of tumor size in patients with invasive breast carcinoma. Material and Methods Data from 307 invasive breast carcinomas were analyzed retrospectively. Preoperative breast MRI was reviewed for size, lesion type, morphology, and dynamic contrast-enhanced tumor kinetics. MRI tumor size was compared with tumor size measurements from the pathologic analysis. Concordance was defined as a difference in diameter of ≤ 0.5 cm. MRI-pathology concordance was compared according to clinical and histopathologic features. Results The mean tumor size on MRI was 2.48 ± 1.41 cm. Tumor measurements determined by MRI were not significantly different from those recorded in the pathologic reports (2.56 ± 1.61 cm, P = 0.199). MRI-pathology concordance was found in 229/307 (74.6%) cases; the size was overestimated in 36 (11.7%) tumors and underestimated in 42 (13.7%). On univariate analysis, MRI-pathology discordance was associated with larger tumor size ( P < 0.001), estrogen receptor (ER) negativity ( P = 0.006), and lymphovascular invasion ( P = 0.003). Human epidermal growth factor receptor 2 positive molecular subtype showed worse correlation between the tumor size measured by MRI and pathology compared with luminal A and luminal B subtypes ( P = 0.008 and 0.007). On multivariate analysis, tumor size and ER status significantly influenced MRI-pathology concordance ( P < 0.05). Conclusion ER negativity and larger tumor size were strongly associated with MRI-pathology discordance in invasive breast carcinomas. Awareness of these factors might improve surgical planning.