The aim of this preregistered EEG study was to show how expectations about enhanced or impaired performance through transcranial stimulation affect feelings of agency and error processing. Using a single-blind experimental design, participants (N = 57) were attached to a transcranial direct current stimulation (tDCS) device, and in different blocks, they were verbally instructed to expect enhanced or impaired cognitive performance, or no effects of the brain stimulation. In all cases, but unbeknownst to the participants, we used an inert sham tDCS protocol. Subsequently, we measured their response to errors on a cognitive control task. Our expectancy manipulation was successful: participants reported improved subjective performance in the enhancement compared with the impairment condition—even though objective performance was kept at a constant level across conditions. Participants reported the highest feelings of agency over their task performance in the control condition, and lowest feelings of agency in the impairment condition. The expectancy manipulation did not affect the error-related negativity (ERN) in association with incorrect responses. During the induction phase, expecting impaired versus enhanced performance increased frontal theta power, potentially reflecting a process of increased cognitive control allocation. Our findings show that verbally induced manipulations can affect subjective performance on a cognitive control task, but that stronger manipulations (e.g., through conditioning) are necessary to induce top-down effects on neural error processing.
Introduction Analysis of covariance (ANCOVA) remains a widely misunderstood approach for dealing with group differences on potential covariates (Miller & Chapman, 2001). This misunderstanding of the ANCOVA has a long history and its discussion is dispersed across fields and journals, making it difficult to obtain a systematic overview. Here we present a network method to organize the results of a literature search conducted by 44 Master's students as part of the 2016 University of Amsterdam course "Good Research Practices". The ANCOVA Pitfall Dora wants to assess whether, in her own university, men earn more than women. She has access to the salaries of a subset of researchers, and, as expected, men earn significantly more than women (p < .005). But wait! The men in her sample are also older than the women, and this confounds the results: perhaps the salary difference is due to age rather than gender. To address this confound and "control for" age, Dora includes age as a covariate in an ANCOVA. This procedure is tempting but statistically problematic. The ANCOVA is easier to interpret correctly when age influences salary but does not differ across the groups. As explained in Miller and Chapman (2001; but see chapter 10 in Judd, McClelland, & Ryan, 2011, and Field, 2013, pp. 484-486), when groups differ on a covariate (e.g., age), removing the variance associated with the covariate also removes the shared variance associated with the group (e.g., gender). As a result, the grouping variable loses some of its representativeness. This occurs mostly when groups are pre-existing and are not obtained by random assignment (Jamieson, 2004). As an example, assume one has access to the height of several mountain peaks in the Himalayas and the Pyrenees (Cohen & Cohen, 1983). One may test whether the mountain ranges differ in height and it may be tempting to include air pressure as a covariate; after all, air pressure differs across the
There are currently no old-age specific interventions for autistic adults. Therefore, in this explorative study, we examined the possible effects of a co-designed psychoeducation program for older autistic adults (55+ years), with a multiple case study design ( N = 9, age 56–73 years; Netherlands Trial Register (code Trial NL5670)). For each participant, also a person close to them (a proxy) participated. This allowed us to calculate a discrepancy score regarding autistic traits and cognitive challenges. The main hypothesis was that our program, delivered after general psychoeducation, would result in a discrepancy reduction between self and proxy reports. However, contrary to our hypothesis, we observed neither intervention effects on our primary outcome measures (discrepancy scores) nor the secondary outcome measures (mastery, self-efficacy, self-esteem, self-stigmatization, quality of life, and hope and future perspectives). Thus, despite co-designing the current intervention, the results were not promising. However, the positive feedback and suggestions of the participants make developing an improved version of a specific psychoeducation program for older autistic adults still a worthwhile pursuit. Lay abstract After receiving an autism diagnosis by a clinician, psychoeducation (i.e. information regarding autism) is often offered. However, older autistic adults (55+ years) may need specific information about the challenges they face in daily life as they are in a specific life phase. A psychoeducation program for this specific age group does not exist yet. We first developed such a program together with autistic adults and clinicians working with autistic people, after which we tested the program with nine autistic adults (56–73 years) and someone close to them (so-called proxy). Before testing the program, we determined together with autistic older adults what they thought should be the outcome of this intervention in order to state whether it was, indeed, a useful intervention. Earlier studies found that autistic people often think differently about their own autistic characteristics than their proxy. A reduction of this difference could increase mutual understanding. Therefore, the main hypothesis was that the program would decrease this difference with respect to autistic characteristics and cognitive challenges (e.g. memory problems). Another hypothesis was that the program would have a positive impact on a series of other factors, such as self-esteem. The results showed that the program did neither decrease the difference in insight nor the other tested factors. Nonetheless, we believe it is important to keep on working on a psychoeducation program for older autistic adults, because participants informed us the program had still helped them in certain ways and they gave helpful feedback for improvements of the program.
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