Hospitals can supply clinical decision support systems with electronic healthcare record provided by different users and stored in different computer systems. This way, during a diagnosis decision a user can be supported by a remote knowledge database constructed by other users, like, for instance, a reference specialist discussion board. Usually, medical applications scenarios like this use different terminology systems leading to terminological interoperability problems. Still, clinical applications frequently make use of different clinical ontology systems that do not provide semantic types necessary to create a structure to carry shared knowledge database. The lack of this semantic types brings ontology interoperability problems which difficult the support of collaborative clinical decision-making. This paper presents a UMLS interoperable solution to promote clinical applications development intended to contribute with collaborative diagnosis decision, in a distributed computer environment based on service-oriented architecture. This paper still presents a case study to demonstrate DDSOnt usability through the development of a system prototype integrated to a collaborative and multimedia communication distance-learning environment.

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