This article describes the new meta-analysis command metaan, which can be used to perform fixed-or random-effects meta-analysis. Besides the standard DerSimonian and Laird approach, metaan offers a wide choice of available models: maximum likelihood, profile likelihood, restricted maximum likelihood, and a permutation model. The command reports a variety of heterogeneity measures, including Cochran's Q, I 2 , H 2 M , and the between-studies variance estimate b τ 2 . A forest plot and a graph of the maximum likelihood function can also be generated.
Meta-analysis is a statistical methodology that combines or integrates the results of several independent clinical trials considered by the analyst to be 'combinable ' (Huque 1988). However, completeness and user-friendliness are uncommon both in specialised meta-analysis software packages and in mainstream statistical packages that have to rely on user-written commands. We implemented the meta-analysis methodology in an Microsoft Excel add-in which is freely available and incorporates more meta-analysis models (including the iterative maximum likelihood and profile likelihood) than are usually available, while paying particular attention to the user-friendliness of the package.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.