Background: The practice of Pharmacovigilance (PV) and Adverse Drug Reaction (ADR) reporting is very necessary to ensure adequate safety of all drugs in use and is an integral component of post marketing surveillance. Pharmacist, including interns are at a central position in carrying out this important function. Objectives: This study sought to assess the practice of pharmacovigilance and adverse drug reaction reporting and the perceived barriers towards its implementation among pharmacist interns in Nigeria. Methods: This was a cross-sectional study among pharmacist interns in Nigeria. The 18-item semi-structured questionnaires were administered online using simple random sampling with the snowballing technique to recruit the participants and the results were analyzed with IBM SPSS version 25. Descriptive statistics were used to summarize the data. The chi-square test was used to evaluate associations. Results: A total of 450 pharmacist interns participated in this study. The practice of PV and ADR reporting is poor among the respondents, less than 40% of the participants have ever reported ADR before, while only 29.1% have reported ADR since starting their internship program. Only 35.8% said “yes” to documenting ADR. Verbal information (61.1%) is the most widely used method of reporting ADR. Lack of cohesion among healthcare professionals, unavailability of feedback from relevant authorities, and fear of being wrong are the most reported barriers towards PV and ADR reporting among the participants. This is a correlation between the number of months spent in internship program and the practice of PV by the participants. ‘Fear of being wrong’ is an essential barrier to PV and ADR reporting among participants in tertiary hospitals (86.0%). Conclusion: The practice of pharmacovigilance is poor among the participants. Many barriers also affect ADR reporting among the interns. Measures should be taken to encourage ADR reporting and the reported barriers should be reviewed to improve pharmacovigilance activities.
Background Pharmacovigilance (PV) and adverse drug reaction (ADR) reporting is at the core of the services and functions of a pharmacist. Pharmacist interns undergoing their one-year mandatory internship program are expected to be armed with this tool kit in order to provide adequate pharmaceutical services in all areas of pharmacy practice. Objectives This study sought to assess the knowledge and perception of pharmacovigilance and adverse drug reaction reporting among pharmacist interns in Nigeria. Methods This study was a cross-sectional study among pharmacist interns in their one-year mandatory internship program across Nigeria. The 32-item semi-structured questionnaires were administered online using simple random sampling with the snowballing technique to recruit the participants in the study. The results were analyzed with IBM SPSS version 25. Descriptive statistics were used to summarize the data. The Chi-square test and contingency coefficient were used to determine the association between knowledge of PV and the demographics of the participants. Results A total of 450 pharmacist interns participated in this study. The participants' knowledge of pharmacovigilance and ADR is 92.5%. About 96.2% of respondents feel that responses to newly released pharmaceuticals must be recorded, compared to 79.1% for older drugs already on the market. There is a high correlation between the duration of the internship program and understanding of PV and ADR reporting among participants. More than fifty percent of respondents concur that ADR reporting is critical, while more than eighty percent concur that ADR reporting is required for pharmacists, the most significant health professionals in ADR reporting. The participants' length of participation in an internship program and their internship location significantly impact their opinion of ADR reporting. Seventy-four percent (74%) of respondents from tertiary hospitals say their internship center encourages ADR reporting. Conclusion Most participants have a solid understanding of PV and ADR reporting, but perceptions of PV and ADR reporting are substantially correlated with internship location and program length. Active measures should be implemented to ensure that all pharmacy interns comprehend and embrace PV and ADR reporting as their exclusive duty.
<p class="abstract">Around 40% of the 210 million human conceptions occurring globally each year are unplanned. Contraception involving the use of devices, medications, and sexual techniques have been the bail out. This has empowered women to make positive decisions about their life and sexual health. Various methods of contraception in use today include the barrier method, the fertility awareness method, hormonal method and permanent contraception. In the United States and in most parts of the world, oral contraceptives (OC) have been the most used contraceptive method. Their use however comes with its pros and cons. OC failure is already an issue of concern in the reproductive health of women. More serious concerns are the impact of the use of these OC's on the woman's quality of life. Women all over the world are becoming increasingly conscious of the ability of OC to either aid or interfere with their health and overall well being. There is paucity of data in recent times looking critically at how OC has been a factor in altering the quality of life of women. Hence this review highlights contraceptive preferences of women, Success and failures of OC use, perception of women towards OC and how the use of OC has impacted their quality of life. Overall, contraceptives have a positive impact on the quality of life of women due to many other benefits it offers apart from contraception including relief of menstrual blood loss, dys-menorrhea, and premenstrual syndrome.</p>
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