Abstract:Background:

The sensing characteristics of a Bragg grating imprinted in a specially developed highly birefringent side-hole fiber were investigated in detail. We showed that such a grating has almost identical sensitivities to temperature for both linearly polarized modes LP01(x) and LP01(y) (approximately 5.9 pm/K) and significantly different sensitivities to hydrostatic pressure (-1.93 pm/MPa for LP01(x) and +5.37 pm/MPa for LP01(y) mode). The sensitivity differences versus mode polarization are so high that this effect can be employed for simultaneous sensing of temperature and pressure by interrogation of the wavelength shifts at LP01(x) and LP01(y) modes. Applying interferometric methods, we also measured the sensitivity of the host side-hole fiber to temperature and hydrostatic pressure for each polarization mode. Our results show that there is good agreement between the normalized sensitivities of the host side-hole fiber and those of the grating for the same polarization modes.

Abstract:Growing interest in the biological activity of aminobisphosphonates has stimulated the development of methods for their synthesis. Although several general procedures were previously elaborated to reach this goal, aminobisphosphonate chemistry is still developing quite substantially. Thus, innovative modifications of the existing commonly used reactions, as well as development of new procedures, are presented in this review, concentrating on recent achievements. Additionally, selected examples of aminobisphosphonate derivatization illustrate their usefulness for obtaining new diagnostic and therapeutic agents.

A method for measuring the sensitivity of Bragg gratings to external parameters for different spatial and polarization modes is presented together with the results of measurements of sensitivity to temperature and elongation for LPx01, LPy01, LPx11 and LPy11 modes. The difference in response according to the type of mode shows the possibility of performing simultaneous temperature and elongation measurements using two-mode Bragg gratings.