Acne vulgaris is a skin disease that often occurs in adolescence and in young adulthood. The main pathogenic factors are hyperkeratinization, obstruction of sebaceous glands, stimulation of sebaceous gland secretion by androgens, and bacterial colonization of sebaceous units by Cutibacterium acnes, which promotes inflammation. Little is known about the role of skin immune cells in the development of acne lesions. The aim of the study was to try to understand the role of skin immune cells in the course of acne. Recent studies have shown that there are at least four major pathways by which Cutibacterium acnes interacts with the innate immune system to induce inflammation: through TLRs, activating inflammasomes, inducing the production of matrix metalloproteinases (MMPs), and stimulating antimicrobial peptide (AMP) activity. Cells of adaptive immune response, mainly Th1 and Th17 lymphocytes, also play an important role in the pathogenesis of acne. It is worth emphasizing that understanding the role of the skin’s immune cells in the pathogenesis of acne may, in the future, contribute to the application of modern therapeutic strategies that would avoid addiction to antibiotics, which would alleviate the spectrum of resistance that is now evident and a current threat.

IntroductionContemporary people do not follow the civilisation development in every life domain, their lifestyle is not always healthy. Self-efficacy is the factor that plays an important role in undertaking actions towards struggling with the disease.The aim of the studyThe aim of the study was to determine the relationship between the general self-efficacy level and health behaviours as well as chosen sociodemographic features in women over the age of 45 years who have undergone osteoporosis treatment.Material and methodsThe study comprised 151 women over the age of 45 years. The research was conducted in 2016 in health care centres in Lublin, a city in south-eastern Poland. The Generalised Self-Efficacy Scale (GSES) by R. Schwarzer, M. Jerusalem and Z. Juczyński and an original questionnaire were used as research tools. The obtained material was subjected to descriptive and statistical analysis. χ2 test, Kruskal-Wallis test, Mann-Whitney Test and Spearman’s rank correlation coefficient were all applied.ResultsThe analysis of obtained results showed that as much as 73.5% of the respondents showed very low and low generalised self-efficacy level. On the other hand, only 22.5% of the examined were characterised by high and very high generalised self-efficacy level. The longer the duration of osteoporosis treatment (rho = 0.251; p = 0.002) and the better the self-estimation of health status (rho = 0.473; p = 0.000), the higher the respondents’ generalised self-efficacy level. The women’s self-efficacy level declined with increasing ailments (rho = –0.190; p = 0.019).ConclusionsThe generalized self-efficacy level and the health behaviours are not satisfactory.

IntroductionOsteoporosis is an illness characterized by the handicapped endurance of the bones, causing an increased risk of fracture.Aim of the studyAim of the study was to establish the level of knowledge about osteoporosis prevention among women screened by bone densitometry and to answer the question whether the level of knowledge is dependent on socio-demographic factors.Material and methodsThe research was realized by means of a survey method, a poll technique in 2014. The study involved 292 women aged 51-83. The examined women were patients undergoing bone densitometry in the healthcare centres in Lublin. The osteoporosis knowledge test (OKT, revised 2011) by Phyllis Gendler was used as a research tool. Gathered material was subject to descriptive and statistical analysis. Tukey's test, t-Student test and variance analysis (ANOVA) were all applied. A statistical significance level was set at α = 0.05.Results and conclusionsRespondents presented the basic exercise knowledge (M = 9.97) and low knowledge concerning risk factors, screening and treatment of osteoporosis (M = 7.87). The calcium knowledge remained on an average level (M = 14.03). Better educated women, city inhabitants as well as women having very good or good social and welfare conditions showed a significantly higher level of knowledge about osteoporosis prevention. Even women undergoing bone densitometry examination present insufficient knowledge about osteoporosis prevention.

When faced with a chronic disease such as rheumatoid arthritis, the patient attempts to cope with the stressful situation by applying coping strategies. The main aim of rheumatoid treatment is not only improving health but also increasing the quality of life. The research objective was to determine the relationship among socio-demographic factors, duration of the disease and its associated ailments, attitude to the disease, self-assessment of one's knowledge of RA, and the application of coping strategies in stressful situations by women with rheumatoid arthritis. The study involved 193 patients of the Clinic of Rheumatology and Systemic Connective Tissue Diseases, and the Rheumatology Unit of the Specialist Outpatient Clinic of the Independent Public Teaching Hospital No. 4 in Lublin, from November 2016-June 2017. The Coping Orientations to Problems Experienced Inventory (COPE) Questionnaire and an author's Original Questionnaire were used in the study. Analysis of variance (ANOVA) and Tukey's range test were applied for statistical analysis. A p-value<0.05 defined the statistical differences. Analysis was performed using the commercial SPSS Statistics 19 software (IBM Corp., Armonk, NY, USA). The respondents usually use instrumental social support (11.5±1.7), focus on and vent emotions (11.4±1.9), use emotional social support (11.4±1.8), employ active coping (11.4±2.1) and positive reinterpretation and growth (11.2±1.8), and least often rely on their sense of humour (5.5±1.4) or use alcohol or drugs (5±1.1). The factors which determine the types of strategy used are age, education, the duration of the disease, ailments experienced, and attitude towards the disease. Those respondents who declared a greater knowledge of RA more often applied positive reinterpretation and growth, and more rarely used alcohol or drugs. In the treatment and rehabilitation processes it is important to reinforce in the patient positive expectations for the treatment, seek advantages and benefits in one's present health status, and educate patients about the disease, its therapy and appropriate coping strategies.

Introduction and objective. Osteoporosis constitutes one of the relevant health, social and economic problems of the contemporary world which concerns 200 million women, of whom about 20-25% will experience a bone fracture. The aim of the study was to learn about the health beliefs and sense of self-efficacy in peri-and post-menopausal women regarding the prevention of osteoporosis. Materials and method. A group of 300 randomly chosen women aged 45-65 who were patients of healthcare centres in Chełm, Lublin, and the surroundings of Zamość (eastern Poland), was examined. Own Health Beliefs Scale (OHBS) associated with Osteoporosis and Own Efficacy Evaluation Scale (OSES) were used for the study. The obtained material was subjected to descriptive and statistical analysis. Tukey test, t-student test and variance analysis (ANOVA) were all applied. A P value less than 0.05 was considered statistically significant. Results were analysed using the SPSS version 19 software package. Results and conclusions. It was stated that respondents had thought that osteoporosis is an averagely serious health problem, and they did not feel peculiarly exposed to falling ill with the disease. They attached great significance to the benefits of physical activity and correct nutrition. The perception of barriers to calcium intake and everyday exercise was moderate. Health motivation remained at the average level. Socio-demographic conditions influenced the respondents' health beliefs in a statistically significant way. Sense of self-efficacy from the aspect of taking possible action preventing osteoporosis remained on the average level; in addition, respondents more often declared the desire for a change in eating habits than resorting to physical activity.