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Despite substantial evidence of the crucial role protein calorie malnutrition (PCM) plays in the occurrence of complications, increased length of stay, and cost of care in hospitalized populations, no standard approach for screening and monitoring the nutritional status of patients initially and throughout admission currently exists. Recognizing that there is a growing public and professional recognition of the importance of malnutrition, a large patient population (30-55%) at risk for PCM, and an even larger population experiencing declining nutritional status during hospitalization, this study examined the feasibility of a full-scale study to assess the value of two biochemical markers, transthyretin and albumin, for detecting and monitoring PCM in hospitalized patients. It was demonstrated that these two markers do provide important information predictive of outcomes for those they identify at risk for PCM. The patients who entered the study with or developed low transthyretin and albumin experienced poorer health outcomes and higher costs of care. Their discharge occurred in an early phase of recovery, with significant implications for after-discharge care. The full-scale study must consider severity of illness and other confounders during randomization and, preferably, be conducted in institutions that currently do not use transthyretin for nutrition assessment.

61separation effect for preparing orthohydrogen or (orthohydrogen) and 33l/s% (paradeuterium), paradeuterium. The method should be consider-and they have so far not been prepared in pure ably simpler and more efficient than the fractional form. distillation of liquid hydrogen. These modifica-Acknowledgment.-The author is much indebted t'ions are a t equilibrium a t no temperature in the to the National Research Council of Canada for a gas phase in concentrations greater than 75% postdoctorate fellowship.Comparison of the infrared spectra of aluminum hydroxylaurate and aluminum deuterosylaurate, and the spectra of aluminum hydroxy-2-ethyl-hexanoate and aluminum deuteroxy-2-ethyl-hexanoate showed that absorption at 2.7 p in aluminum hydroxy soaps, ascribed to free OH, is replaced by absorption at 3.67 p in aluminum deuteroxy soaps, the spectra of soaps of the corresponding acid being otherwise similar. -4bsorption at 1 0 . 1 1~ in aluminum soaps was shifted to 10.24~ for gallium laurate and to 1 0 . 3 1~ for indium laurate. The spectra were otherwise similar, except for small shifts in the 6 . 3 3~ absorption band of aluminum soaps. Absorption a t 10.14~ in aluminum soaps was ascribed t o the aluminum-oxygen linkage. \Vhen infrared absorption a t 2 . 7~ is shown by aluminum soaps it occurs also in the aluminum soap-cyclohexane gels, indicating that gelation is independent of bonded hydroxyl. Intensity of absorption at 10.14~ for a series of gels of constant concentration of aluminum dilaurate in benzene was found to decrease with the amountJ of added i+cresoI, showing that modification of the bond in aluminum soaps causing absorption a t 10.14~ is nssockited with loss in viscosity of gels caused by cresols.

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