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Methylene blue is an intravenously administered agent that may potentiate serotonin syndrome. The usage of methylene blue to evaluate ureters for injuries and patency during urological surgeries is recognized as common practice. However, there is no mention of serotonin syndrome caused by methylene blue in urological literature or for urological surgery. We report the first urological case in order to raise awareness of the risk for serotonin toxicity with utilizing methylene blue.

At baseline, performance was poor at achieving target forces specified by national guidelines. Simulation-based training improved the success rate, but no participant achieved the predefined threshold for proficiency.

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(Anesth Analg. 2019;128:109–116) Cricoid pressure (CP) force has been suggested as a protective means of preventing aspiration of gastric contents during anesthesia. It is widely used for rapid sequence intubation (RSI). Current national guidelines recommend the use of 10 N when the patient is awake, increasing to 30 N once the patient loses consciousness (LOC). However, studies have shown that few clinicians are proficient at achieving such targets, and individual learning curves during simulation training have not been studied. In the present study, the authors determined the extent to which experienced clinicians accurately apply force targets and established individual learning curves during training on a CP simulator.