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in the analysis. Nearly 39% (8109) patients were over age 65. Since trials were of varying durations, we report event rates as incidence per 100 patient-years of exposure. Results Of the 27,039 patients studied, 15,071 received meloxicam in doses of 7.5 ? 30 mg daily. A total of 11,078 patients took diclofenac, naproxen or piroxicam. An additional 736 patients were randomised to placebo. The number of patients with cardiovascular and renal events adverse events is shown in the Table 1 below. Incidence rates in parenthesis refer to rates per 100 patient years. Abstract THU0258 Table 1 Meloxicam NSAIDs Placebo Intent-to-treat patients (n = 15,071) (n = 11,078) (n = 736) Patient Years 3129 1202 113 Events Myocardial Infarction 18 (0.58) 8 (0.67) 2 (1.8) Cardiac Failure 15 (0.48) 7 (0.58) 0 (0)