SUMMARYAtrolactic syntheses have been carried out to evaluate the potentiality, in asymmetric syntheses, of chiral inducers. The (d1)-hydroxyhelicenes l, 2, the (dl) sec. alcohols 1-12 and the (d1)phenolic binaphtyl compound have been used as inducers. The d.e. are collected in table I (6-100%). The atrolactic asymmetric synthesis has also been carried out using three optically active inducers, namely : (-)-quinine 13, (-)-l0,ll-dihydroquinine -14, and R(-)-2,2,2-trifluoro-1-(9-anthryl)ethanol 5. Diastereomeric and enantiomeric excesses equal or greater than 88% have been obtained in six cases out of sixteen :(l-naphtyl)-(9-anthryl)methanol 3 (d.e = 90%) ; 2,2,2-trichloro-1-(9-anthryl) ethanol 7 (d.e = 100% ?2), 2,2,2-tribromo-1-(9-anthryl)ethanol 8 (d.e = 100% +2), (-)=quinine 13 (e.e = 95.5%), and (-)-2,2,2-trifluoro-l-(9-anthryl) ethanol 6 (e.e = 88%).

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