Smart materials like piezoelectric polymers represent a new class of promising scaffold in neural tissue engineering. In the current study, the fabrication processing parameters of polyvinylidine fluoride (PVDF) nanofibrous scaffold are found as a potential scaffold with nanoscale morphology and microscale alignment. Electrospinning technique with the ability to mimic the structure and function of an extracellular matrix is a preferable method to customize the scaffold features. PVDF nanofibrous scaffolds were successfully fabricated by the electrospinning technique. The influence of PVDF solution concentration and other processing parameters like applied voltage, tip-to-collector distance, feeding rate, collector speed and the solvent were studied. The optimal parameters were 30 w/v% PVDF concentration, 15 kV applied voltage, 18 cm tip-to-collector distance, 0.5 ml/h feeding rate, 2500 rpm collector speed and N,N′-dimethylacetamide/acetone as a solvent. The mean fiber diameter of the obtained scaffold was 352.9 ± 24 nm with uniform and aligned morphology. Finally, the cell viability and morphology of PC-12 cells on the optimum scaffold indicated the potential of PVDF nanofibrous scaffold for neural tissue engineering.
Silver nanoparticles were produced by irradiating a silver plate with 1064 nm laser beam in pure water. The effect of the laser fluence and ablation time on the ablation efficiency was studied. Fragmentation of the ablated colloid solution by subsequent treatment with 1064 and 532 nm laser pulses yield redistribution of nanoparticles to a smaller mean size.
The dynamics of Au/Ag alloy formation under Nd:YAG
laser irradiation of a mixture of the monometallic colloidal
solutions have been experimentally investigated. The change in
absorption spectrum of the colloidal particles has been studied as
a function of laser irradiation time, fluence, and concentration
of nanoparticles in individual colloids. The characteristic time
of the alloy formation is about 10 minutes, without any
surfactant.
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