Data were collected on 390 patients who attended a dermatology out-patient department in whom a clinical diagnosis of urticaria was made. Two hundred and thirty-seven (61%) were women. The median age at onset of symptoms was 40 years. Sixty-one (16%) had acute urticaria with symptoms of less than 6 weeks duration at presentation. The disorder was deemed idiopathic in 217 (56%) patients, 59 (15%) had physical urticaria and 57 (15%) had both idiopathic and physical urticaria. Thirty-eight (10%) patients reported intolerance to salicylate or similar drugs, and 31 of these 38 patients also had idiopathic symptoms. One hundred and seventy-two (44%) patients reported a good response to treatment with H1 receptor antagonists. Those who gained little or no benefit from these drugs were more likely to have a physical urticaria (P < 0.05) or to report intolerance reactions (P < 0.05). Only 113 (29%) patients were asymptomatic when discharged. One in five of a small sample contacted still had symptoms 10 years after presentation. Patients seen in an urticaria clinic were less likely to have routine investigations performed and more likely to be discharged at first attendance. When compared with previous published surveys, these figures show a lower proportion of intolerance reactions and a greater proportion of patients responding well to treatment with antihistamines.
Summary Appropriate management of urticaria depends on the correct evaluation of clinical patterns and causes where these can be identified. Guidance for treatment is presented, based on the strength of evidence available at the time of preparation. As many of the recommendations relate to the off‐licence use of drugs, it is particularly important that clinicians should be familiar with dosing and side‐effects of treatment in the context of managing urticaria.
These guidelines for management of urticaria and angio-oedema have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of aetiology, diagnosis and investigation.
It has been suggested that skin disease and psychological disturbance may be linked. Recent work has focused on the fatal outcome associated with some dermatological disorders as a result of suicide. The impressions of dermatologists about how much psychological or psychiatric morbidity they see related to dermatological disease has not been addressed. The survey reported here revealed that most dermatologists recognized the relationship and demonstrated the perceived need for clinical psychology and psychiatric services for patients with dermatological disorders. It confirmed the impression that in a small number of cases, skin complaints are associated with attempted or completed suicide.
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