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A method has been developed to determine quantitatively the level of the anti-neurofilament antibodies in the blood of patients affected with different neurological diseases. In 7 out of the 52 patients, taken as controls and in 33 out of the 208 patients affected with neurological diseases, the antibody levels were increased. The increases were greater in 43 patients with Parkinson dementia and amyotrophic lateral sclerosis who originated from Guam. On the other hand, the levels were very low in 10 patients affected with subacute sclerosing panencephalitis and in 11 cases with Chagas' disease. In 24 cases with dementia of Alzheimer type, the levels were normal.

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Problem children have great difficulties, as well to study any kind of language as to study mathematics. Papy F. and Papy G. have described a method to teach mathematics in the primary school. This method, based upon a non verbal language, has been applied to several groups of problem children. It gave them the opportunity to progress a lot in mathematics. We study now the (possible) influence of this method on the evolution of their language and so of their psycho-pathological behaviour.