Currently, the management of pregnant women with carbohydrate metabolism disorders is challenging due to the high risk of unfavorable events both for the mother and the child even in insignificant deviations from the target value. In addition to the conventional methods of self-monitoring, continuous glucose monitoring (CGM) is an important tool to control diabetes. CGM in pregnant women provides the detailed information on the type and trends of the changes in blood glucose levels and the fluctuations of glucose levels and also identifies the episodes of latent nocturnal hypoglycemia and postprandial hyperglycemia. The analysis of CGM data allows for correcting insulin therapy, taking a decision on its initiation, and modifying diet and exercise plan. Multiple studies demonstrate the efficacy of CGM in terms of compensating manifest diabetes. As to gestational diabetes, the eligibility of modern glucose monitoring technologies for the prevention of various complications is still controversial. Further studies on the potential use of these devices in gestational diabetes could provide a basis for increasing their application in routine clinical practice. This will improve the management of pregnant women with carbohydrate metabolism disorders.KEYWORDS: diabetes, gestational diabetes, continuous glucose monitoring, flash monitoring, pregnancy, macrosomia, self-monitoring.FOR CITATION: Ushanova F.O., Demidova T.Yu. Potentialities of modern glucose monitoring devices during pregnancy. Russian Medical Inquiry. 2020;4(6):352–357. DOI: 10.32364/2587-6821-2020-4-6-352-357.

Introduction. According to various authors, uncompensated gestational diabetes mellitus (GDM) is accompanied by the development of many complications affecting the mother and fetus. However, published data on the prevalence of GDM and its complications in real clinical practice in our country are insufficient.Aim. To estimate the prevalence of GDM among pregnant women in the South-Eastern Administrative District of Moscow, to analyze the main risk factors, the features of the course and pregnancy outcomes in women with GDM.Materials and Methods. Retrospective analysis of primary records of 510 pregnant women who were diagnosed with GDM during 2019. A comparative analysis of pregnancy complications and outcomes depending on the age of diagnosis of GDM was performed.Results and Discussion. During 2019, 510 pregnant women out of 5,000 women observed were diagnosed with GSD. The mean age of the women was 31.9 ± 4.8 (95% CI 31.5-32.3). Most frequently, 224 pregnant women (43.9%) were diagnosed in the 1st trimester of pregnancy, 31.8% (162) in the 2nd trimester, and 18.6% (95) in the 3rd trimester. Mean venous plasma glucose values were 5.43 [5.25; 5.7] mmol/L, and glycated hemoglobin was 5.19 ± 0.4% (95% CI 5.15-5.24). Diet therapy was predominantly sufficient to achieve GSD compensation - 84.3%. Complications of pregnancy were observed in 123 women (24.1%). Unfavorable pregnancy outcomes were recorded in 153 women with GSD out of 213 women analyzed (71.8%). There was no statistically significant difference in pregnancy outcomes depending on the age of diagnosis of GDM.Conclusions. The prevalence of GDM in the South-Eastern Administrative District of Moscow was 10.2%, which is consistent with the data of various epidemiological studies in other regions. The development of adverse pregnancy outcomes remains at a high level. Therefore, it is advisable to conduct further research aimed at assessing the main factors influencing the course and outcomes of pregnancy.

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