Chlamydia trachomatis (CT) is a Gram negative bacterium that parasitizes eukaryotic cells, most frequently in the female cervix, causing several consequences to the health of women. It presents two forms, the first called elementary bodies (EC) being the infectious and resistant form that survives in the extracellular environment and the second, called reticular bodies (CR), the proliferative form of the bacterium. CT is a very virulent pathogen, with more than twenty serotypes that cause serious pathologies in humans. The present study sought to estimate the prevalence of Chlamydia trachomatis in the Brazilian population, highlighting the epidemiology, characteristics of the bacterium, the importance of its diagnosis and treatment A literature review was carried out based on studies of articles published between 2009 and 2018, in Portuguese, English and Spanish, with a total of 41 articles selected. In Brazil, the diagnosis and monitoring of infections by this microorganism is not yet a reality and there are few studies related to the theme, showing a high prevalence of the infection. Therefore, the lack of monitoring and diagnosis of this pathogen may lead to future complications, since the long-term result of infection and the promotion of infertility is seen in several studies. Female patients are the most affected by these pathogens, yet complications can be reported in males.
A técnica de cultura celular é utilizada por todas as áreas das ciências, principalmente na área da Biotecnologia por trazer resultados precisos e conhecimentos sobre novas patologias, estudos sobre mecanismos de infecções por microrganismo. O objetivo deste estudo foi analisar o potencial proliferativo da célula Crandell-Rees Feline Kidney (CRFK) em cultura estática com meio de cultura Dulbecco (DMEM) suplementado com coenzimas do complexo B. Tratou-se de um estudo experimental quantitativo, dividido em três grupos: Controle, Diversas e Diversas com B12, onde o grupo Controle não recebeu concentração extra de coenzimas, o grupo Diversas recebeu tratamento com coenzimas do complexo B, sendo elas: tiamina, riboflavina, niacina, ácido pantatênico, piridoxina, biotina e ácido fólico em quatro concentrações distintas, sempre dobrando a concentração existente na bula do meio de cultura DMEM, o terceiro grupo recebeu todas as sete coenzimas do complexo B mais a cianocobalamina (B12) que não está presente na bula do DMEM. A partir deste estudo concluiu-se que, o tratamento com coenzimas do complexo B otimizou o processo de mitose e tempo das subculturas: no grupo Diversas com B12 o tempo de cultura foi de 19,05 horas para atingir o ponto ótimo da confluência quando comparada ao grupo Controle. Portanto, o estudo apontou que a coenzima B12 é essencial para o metabolismo de células, otimizando o tempo de cultura aumentando o potencial de mitose celular.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.