Problem statement:The modern world is based on using physical, biological and social systems more effectively using advanced computerized techniques. A great amount of data being generated by such systems; it leads to a paradigm shift from classical modeling and analyses based on basic principles to developing models and the corresponding analyses directly from data. The ability to extract useful hidden knowledge in these data and to act on that knowledge is becoming increasingly important in today's competitive world. Approach: The entire process of applying a computer-based methodology, including new techniques, for discovering knowledge from data is called data mining. There are two primary goals in the data mining which are prediction and classification. The larger data involved in the data mining requires clustering and outlier analysis for reducing as well as collecting only useful data set. Results: This study is focusing the review of implementation techniques, recent research on clustering and outlier analysis. Conclusion: The study aims for providing the review of clustering and outlier analysis technique and the discussion on the study will guide the researcher for improving their research direction.
Background Optimal COVID-19 management is still undefined. In this complicated scenario, the construction of a computational model capable of extracting information from electronic medical records, correlating signs, symptoms and medical prescriptions, could improve patient management/prognosis. Methods The aim of this study is to investigate the correlation between drug prescriptions and outcome in patients with COVID-19. We extracted data from 3674 medical records of hospitalized patients: drug prescriptions, outcome, and demographics. The outcome evaluated was hospital outcome. We applied correlation analysis using a Logistic Regression algorithm for machine learning with Lasso and Matthews correlation coefficient. Results We found correlations between drugs and patient outcomes (death/discharged alive). Anticoagulants, used very frequently during all phases of the disease, were associated with good prognosis only after the first week of symptoms. Antibiotics very frequently prescribed, especially early, were not correlated with outcome, suggesting that bacterial infections may not be important in determining prognosis. There were no differences between age groups. Conclusions In conclusion, we achieved an important result in the area of Artificial Intelligence, as we were able to establish a correlation between concrete variables in a real and extremely complex environment of clinical data from COVID-19. Our results are an initial and promising contribution in decision-making and real-time environments to support resource management and forecasting prognosis of patients with COVID-19.
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