The objective of this chapter is to provide conceptual understandings of evaluation methods for healthcare and concrete illustrations in order to take stock of the advancements and applications on the subject. The chapter is divided in four sections: the first one sets the stage at a European level by evaluating healthcare system performance; the second goes back to the fundamental principles of methods of evaluation for healthcare; the third one follows with illustrations of patient-centred and person-centred methods of evaluation; and the last part moves forward with a reflection on intangibles and a proposition for a method of observation.