The most recent trend manufacturers have embraced to seek operational performance improvements is the use of a wide range of digital technologies typically associated with Industry 4.0. However, few studies have investigated the relationship between such technologies and the long-established lean manufacturing domain, and how they, together, influence operational performance. Based on data from a cross-sectional survey of manufacturing companies, this study investigates the relationships between the use of lean manufacturing, factory digitalisation, and operational performance using hierarchical multiple regression analysis. While simultaneously controlling for the effects of production repetitiveness, company size, and length of lean manufacturing implementation, the findings show that both lean manufacturing and factory digitalisation individually contribute to improved operational performance. Furthermore, it is found that when used together, they have a complementary (or synergistic) effect that is greater than their individual effects combined. These research findings provide both theoretical and practical insights into how lean manufacturing and factory digitalisation affect the operational performance of manufacturing firms. In light of the upcoming fourth industrial revolution, these findings suggest that lean manufacturing is not obsolete but rather is more important than ever in order to reap the benefits from emerging technologies and translate them into improved operational performance.

Manufacturing flexibility improves a firm's ability to react in timely manner to customer demands and to increase production system productivity without incurring excessive costs and expending an excessive amount of resources. The emerging technologies in the Industry 4.0 era, such as cloud operations or industrial Artificial Intelligence, allow for new flexible production systems. We develop and test an analytical model for a throughput analysis and use it to reveal the conditions under which the autonomous mobile robots (AMR)-based flexible production networks are more advantageous as compared to the traditional production lines. Using a circular loop among workstations and inter-operational buffers, our model allows congestion to be avoided by utilizing multiple crosses and analyzing both the flow and the load/unload phases. The sensitivity analysis shows that the cost of the AMRs and the number of shifts are the key factors in improving flexibility and productivity. The outcomes of this research promote a deeper understanding of the role of AMRs in Industry 4.0-based production networks and can be utilized by production planners to determine optimal configurations and the associated performance impact of the AMR-based production networks in as compared to the traditionally balanced lines. This study supports the decision-makers in how the AMR in production systems in process industry can improve manufacturing performance in terms of productivity, flexibility, and costs.

Traditionally, packaging design has had a subordinate role with respect to product design and production systems design; however, its impact on supply chain costs and performances can be devastating. Only in the past few years its strategic role has been recognized both in theory and in practice. Although packaging design research attracted considerable attention in the recent past, the purpose of this article is to broaden the field even further in two main directions. First, an attempt is made to review the status of literature on packaging design: a total of 89 articles published between 1990 and 2011 are reviewed and classified by content. In this contest, related International Standards are also presented and discussed, and a conceptual framework for packaging design is presented. Second, an agenda for future research in this area is provided

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