Summary Background Information about SARS‐CoV‐2 infection in HIV‐infected individuals is scarce. Methods In this prospective study, we included HIV‐infected individuals (PLWHIV) with confirmed SARS‐CoV‐2 infection and compared them with PLWHIV negative for SARS‐CoV‐2. Results we compared 55 cases of SARS‐CoV‐2 infection with 69 asymptomatic PLWHIV negative for SARS‐CoV‐2 RT‐PCR and/or serology. There was no significant difference between SARS‐CoV‐2 positive or negative patients for age distribution, gender, time with HIV infection, nadir CD4‐cell counts, type and number of co‐morbidities, current CD4 and CD8 counts and type of anti‐HIV therapy. Positive patients presented with a median of 3 symptoms (IQR 1‐3). Most common symptoms were fever (76%), dyspnoea (35%), anosmia (29%) non‐productive cough (27%), fatigue 22%) and ageusia (20%). Ten patients (18%) were completely asymptomatic. Four (7.2%) subjects died of COVID‐19. Factors significantly (P<0.05) associated with death included age and number of co‐morbidities, while time from HIV infection and lower current CD4 counts were significant only in univariate analysis. Conclusion HIV‐infected individuals are not protected from SARS‐CoV‐2 infection or have a lower risk of severe disease. Indeed, those with low CD4 cell counts might have worse outcomes. Infection is asymptomatic in a large proportion of subjects and this is relevant for epidemiological studies. This article is protected by copyright. All rights reserved.
The proportion of new diagnoses of HIV infection in immigrants residing in Italy raised from 11% in 1992 to 29.7% in 2018. To investigate the HIV clades circulating in this community a retrospective study was performed in 557 HIV-infected immigrants living in 12 Italian cities. Immigrants originated from East-Europe and Central-Asia (11.7%), North Africa and Middle East (7.3%), South and SouthEast Asia (7.2%), Latin America and the Caribbean (14.4%), and sub-Saharan Africa (59.4%). More than 87% of immigrants were on antiretroviral therapy (ART), although 26.6% of them were viremic. A 22.0% of immigrants had hepatitis (HBV and/or HCV) and/or tuberculosis. HIV phylogenetic analysis on sequences from 192 immigrants showed the presence of clades B (23.4%), G (16.1%), C (10.4%), A1 (9.4%), F1 (5.2%), D (1.6%) and Circulating Recombinant Forms (CRFs) (33.9%). CRF02_AG represented 72.3% of the total CRFs. Clusters between immigrants and Italian natives were also present. Drug resistance mutations to NRTI, NNRTI, and PI drug classes occurred in 29.1% of ART-treated and in 12.9% of ART-naïve individuals. These data highlight the need for tailored public health interventions in immigrants to avoid spreading in Italy of HIV genetic forms and ART-resistant variants, as well as HIV co-morbidities.
BackgroundMigrants in Italy are prevalently young adults, with a higher risk of sexual transmitted infections (STI) and HIV infection. Promoting consistent as well as correct use of condoms could reduce failure rate due to their improper use. The aim of our study was to evaluate Condom Use Skills among a migrant population recently landed in Italy, hosted in a government center for asylum seekers.MethodsThe study sample was composed of 80 male migrants. Sanitary trained interviewers submitted a questionnaire to participants to investigate age, provenience, marital status, educational level and knowledge about transmission and prevention of HIV/STI. Then, we assessed participants’ level of condom use skill with the Condom Use Skills (CUS) measure by using a wooden penile model. The interviewer filled in a checklist and assigned 1 point for correct demonstration of each behavior that may prevent condom failure during sex.ResultsParticipants’ median age was 26 years and the sample was composed of 54 migrants from sub-Saharan Africa and 26 from Middle East. Most of them were married, with a lower middle level of education, up to 8 or 5 years. Half of the sample achieved the highest score in the questionnaire and our CUS showed a large number of people with middle high score classes. The Spearman’s rho was 0.30, therefore answers to the questionnaire and CUS score appeared correlated (p < 0.05). In the multivariate model, to have a higher CUS score resulted to be associated to be older than 26 years (p < 0.05), with a higher level of education (p = 0.001), and a higher score in the questionnaire (p < 0.05). There were no significant differences in the level of CUS between single or married men and between African and Middle Asian migrants of the sample.ConclusionsOur study shows that educational level influences the quality of knowledge and awareness about STI/AIDS and contribute to correct condom use. Since the half of participants had a low educational level and linguistic problems, the risk of missing campaigns messages or misunderstanding informative materials increases. Direct observation of condom-application on penile model may offer realistic assessment of application skills in these individuals.Electronic supplementary materialThe online version of this article (doi:10.1186/s13104-017-2520-1) contains supplementary material, which is available to authorized users.
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Um dos grandes desafios no campo educacional atual é articular as possibilidades geradas pelas mídias e tecnologias a fim de potencializar os processos políticos e estéticos dos conteúdos escolares de uma sociedade em constante transformação. A formação inicial – e continuada – deve oportunizar o enfrentar desse desafio para que tenhamos implicações da utilização dessas tecnologias no contexto escolar. Este escrito é um relato de experiência que disserta sobre a utilização das Tecnologias Digitais de Informação e Comunicação (TDICs) para mediar o processo didático pedagógico das “práticas corporais” junto ao processo formativo de professores de Educação Física da Universidade Federal de Sergipe (UFS). O texto se propõe contar três experiências: (1) vídeo-minuto, (2) tutorial para ensino das provas de atletismo e (3) as experiências com o cinema/audiovisual em disciplinas específicas. Conclui-se que o tempo presente exige a abertura àquilo que a mídia-educação, enquanto conhecimento e prática pedagógica, oferece ao campo educacional e investigativo. As experiências aqui relatadas foram pensadas no sentido de impactar nas práticas pedagógicas desses futuros professores quanto atuarem, posteriormente, na escola.
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