Background: Distal diabetic sensorimotor polyneuropathy is a common complication occurred in diabetes mellituspatients. Even though the number of diabetes mellitus patients has been increasing, the prevalence is still far from its actual numbers due to diagnostic and method criteria. Objectives:We aimed to determine Toronto Clinical Neuropathy (TCN) and modified Toronto clinical neuropathy (mTCN) scores in distal diabetic sensorimotor polyneuropathy patients. Methods: Cross-sectional study was carried out from October 29 th , 2014-June 1 st , 2015 in 77 diabetes mellitus patients who visited Outpatient Clinic. Polyneuropathy diagnosis was based on TCN and mTCN scores, with gold standard of peroneal and/or sural nerve conduction velocity examination.

Background and Objective. The poor control of blood glucose levels in patients with diabetes mellitus is a major risk factor from various complications of diabetes mellitus, such as polyneuropathy. One of the nerves that are often affected in the case of diabetic neuropathy is the peroneal nerve. This study aimed to determine the association between blood glucose level control measured with serum hemoglobin A1c (HBA1c) levels with peroneal motor nerve conduction velocity in type 2 diabetes mellitus patients with polyneuropathy.Methods. The study was conducted on diabetic neuropathy patients who fulfilled inclusion and exclusion criteria in neurology unit and diabetes unit Dr. Soetomo General Hospital Surabaya on a consecutive basis from February to July 2013. The serum HbA1c level and nerve conduction velocity in peroneal motor nerve were examined; then, the results were grouped into two groups which were serum HbA1c <7% and ≥7% and NCV in normal and low peroneal motor nerve Results. There were 26 subjects, consisting of 6 subjects with serum HbA1c <7% and 20 subjects with serum HbA1c ≥ 7%. There was an association between blood glucose level control measured by serum HbA1c levels and NCV in peroneal motor nerve with statistical significance of p = 0.0018 (Odd ratio 15; 95% IK 1.397 -161.045). Conclusion.There was an association between blood glucose level control measured by serum HbA1c levels with NCV in peroneal motor nerve in type 2 diabetes mellitus patients with polyneuropathy.

Background: Fatigue is a common symptom and has a greater effect on daily living of myasthenia gravis (MG) patients than has muscle weakness. Latest evidence suggested that fatigue in MG negatively impact disease severity. The relationship between fatigue level with disease severity has never been explored in MG patients. Aims. The study aimed to determine the association between fatigue level and disease severity in myasthenia gravis patients at Dr. Soetomo Public Hospital Surabaya. Method. A cross-sectional was used in this research. Participants of the research were patients with myasthenia gravis in Neurology Clinic, Dr. Soetomo Public Hospital Surabaya. The period of data collection was from April to June 2021. Fatigue level measured with Fatigue Severity Scale (FSS) questionaire and disease severity measured with Myasthenia Gravis Composite (MGC) score. Data analysed using SPSS version 22.0 with significances of p <0.05. Results. There were 37 participants consisted of 14 males and 23 females. Mean age of participants 45,03 ± 11,69. Mean age of onset was 40,38 ± 12,60. The mean FSS was 4,02 ± 1,93 and mean MGC was 5,24 ± 5,64. From all participants, we found that about 24 patients (64,9%) showed severe fatigue and 22 patients (58,5%) have severe disease status. The Chi-Square correlation test analysis indicates a significant association between FSS mean score and MGC mean score (p = 0.009, OR at 6,750) 95% CI (1,51-30,16). Conclusion.There was an association between fatigue level and disease severity in myasthenia gravis patients.