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SummaryThe aggregation of platelets collected from maternal/neonatal pairs (n = 240) at the time of childbirth, was studied in response to multiple doses of ADP, collagen, arachidonic acid and ristocetin. Similar responses were obtained from healthy nonpregnant adult controls for comparison. The lag phase, slope of the aggregation curves as well as maximum aggregation (MA%) were recorded and analysed. Neonatal and adult platelets exhibited more enhanced responses to decreasing doses of ADP, arachidonic acid and ristocetin, than maternal platelets. These enhanced responses were exhibited more consistantly in the slopes of the aggregation curves than in MA%. Although neonatal platelets have shown longer lag phase in their responses to collagen, the rate of the aggregation reaction was significantly faster than maternal platelets, with no differences in MA%. These results contradict many previous reports suggesting impaired aggregation responses of neonatal platelets to these agonist. The possible reasons for these contradictions were discussed.

The use of contraceptives can have an impact on better spacing between children, better child care, improvement of children's health and preservation of the mother's health. In this study 2675 Saudi women attending a gynaecology out-patient clinic were interviewed about their contraceptive practices. The majority of the women (56.0%) were using or had used some form of contraceptive. Oral contraceptives were the most common method; 94.8% of the 1497 women who practised contraception were using or had used this form of contraception. Sterilization accounted for 0.9% of contraceptive practices, while the intrauterine device was a more common form of contraceptive among the more educated women.

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Forty-five (45) cases of ectopic pregnancy are reported, an incidence of 1:742 pregnancies. Approximately (40%) of these patients gave a positive history of infertility, pelvic infection or abdominal surgery. Eighty-five percent (85%) of the cases were among gravida 1-5; nullipara and grand-multipara constituted the low-risk group. In 88% of the cases, the pregnancy was tubal ectopic, with 58.5% in the right fallopian tube. History of amenorrhea and lower abdominal pain with tenderness were the presenting features in 95% of the cases, while vaginal bleeding was reported by 50%. Vaginal examination is singled out as of poor diagnostic value, and laparoscopy is found to be the best diagnostic procedure. The pertinent medical literature is reviewed.