Summary Background Saudi Arabia's Vision 2030 represents a major structural shift in all economic sectors. Health care is one of the largest sectors significantly contributing to achievement of the vision Objectives To provide an overview of health workforce in Saudi Arabia and identify various critical issues and challenges that need to be addressed in achieving health system goals envisaged in the Vision. Methods This paper is based on extensive review of literature conducted to stimulate pertinent descriptive information on health workforce in Saudi Arabia. Findings Saudi nationals constitute 44% of all health workforce and 29.5% of all physicians employed by the health system. Among Saudi nationals, there is a significant underrepresentation of females except in the nursing profession. The health workforce is beleaguered with numerical inadequacy, skill imbalance, gender disparity, and access issues. Conclusion Health system needs to adopt a rigorous approach by investing heavily on medical, nursing, and other specialized fields of education. Planning for the health workforce needs to adopt appropriate strategies that reflect all aspects including the number, skills, and gender distribution for meeting the future health needs of population to facilitate achievement of Vision.

This study investigates the factors that affect traffic safety in the Qassim region. A questionnaire was developed on the basis of the Handbook of road safety and consisted of 85 items measuring seven dimensions: area-wide traffic calming (22 items), vehicle design and protective devices (26 items), road design (24 items), road maintenance (three items), traffic education (four items), police campaigns and sanctions (three items), and post-accident care (three items). A sample encompassing 1,500 Qassim University students, and visitors was randomly selected to collect data. A total of 1,500 questionnaires were distributed to students, and visitors of which 1,053 were retrieved. The elimination of data outliers resulted in a sample of 909 subjects. The results pointed out a moderate level of traffic safety in the Qassim region. Furthermore, 10 leading causes of road traffic accidents emerged, namely, excess speed, irregular bypasses, irregular rotations, lack of prioritization of other drivers, irregular stops, lack of road readiness, driver carelessness, use of a mobile phone while driving, noncompliance with traffic signals, and, finally, nonuse of seat belts. On the basis of these results, conclusions and policy implications were provided.

: Keeping in view the public health-related issues of Alzheimer's disease (AD), its unpredictable occurrence and progression indicate the needs for best treatment options. The present bioinformatics study explores the binding pattern and molecular interactions between human acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes with natural compounds from Bacopa monnieri. The docking analysis between natural compounds as a ligand and AChE, BuChE as a receptor was completed using MGL tools Autodock 4.2 module. The analysis of the hydrophobic interactions, inhibition constants, and hydrogen bonds may indicates that they play a significant role in finding out the interacting position at the active site. However, after analyzing the binding energy (ΔG), the documented data shows that bacoside X, bacoside A, 3-beta-D-glucosylstigmasterol and daucosterol could be good inhibitors in the inhibition of AChE and BuChE activities. Therefore, our study indicates that the inhibition constants of the aforesaid natural compounds of Bacopa can be utilized for the development of inhibitors.

Non-communicable diseases (NCDs) pose critical challenges in achieving Saudi Arabia's Vision 2030. This paper provides an overview of NCDs in Saudi Arabia and identifies various critical issues and challenges in reducing the burden of NCDs. All relevant data for this paper was extracted from existing published literature in various database including Medline, Scopus, ScienceDirect and PubMed. Google Scholar search engine was used to identify papers and reports on relevant literature published after the year 2000. NCDs account for about 73% of all deaths in Saudi Arabia. Deaths due to cardiovascular diseases account for 37% of all deaths, cancers 10%, diabetes mellitus 3% and other NCDs cause 20% of all deaths. Economic costs of NCDs likely to increase with the undesirable life style of youths and increasing share of old population. Further, the shortage of local health workforce, lack of primary health care focus and covid-19 pandemic are likely to affect the government efforts to prevent and control NCDs. Ministry of Health (MOH) needs to play a catalyst role in raising awareness of population through multi-sectoral linkages and policies to reduce the exposure to NCD risk factors. There is a need to review all relevant policy documents to ensure consistency of these policies with prevention and control measures of NCDs.

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