Due to emerging new variants of Corona virus, study of placental histopathological changes helps in understanding its tissue tropism and effects of the virus of maternal and foetal morbidities. Prospective Observational Study.To evaluate and describe histopathologic findings in the placentas of women affected with COVID19. A total of 16 placentas from pregnant women who were infected with COVID-19 in any gestational age and delivering between March 2020 and February 2022 were examined and compared with normal third trimester placentas received in the same time period. Among the 16 placentas examined, most significant change as a sign of maternal malperfusion is increased intervillous fibrin deposition, which is seen in 81.25% cases, followed by infarction, calcification, increased syncytial knots, haemorrhage, calcification, vascular congestion and fibrin thrombi. Most significant foetal malperfusion sign is Chorangiosis which is seen in 37.5% cases, followed by thrombi in umbilical vessels. Also, 25% of the placentas examined showed Villitis, 18.75% showed Deciduitis, 6.25% showed Chorioamnionitis and 6.25% showed vasculitis. COVID-19 placentas show increased prevalence of decidual arteriopathy and features of foeto-maternal vascular malperfusion which can be related to the consequences in foetus like Preterm delivery, IUGR and respiratory distress.

Mass lesions of liver are generally evaluated by Fine needle aspiration (FNA). Aim of present study was to assess the utility of ultrasound guided FNA cytology in the diagnosis of hepatic lesions and to study the cytomorphological features of these lesions and to categorise them as inflammatory, benign and malignant Patients who have been admitted during a period between 2018 to 2021 February with suspected liver diseases were subjected to ultrasound guided FNAC and cytological assessment. Fine needle aspirations of liver were performed on 39 patients. Out of which 26 were suspected by malignant lesions and 13 of non-neoplastic lesions. Of the 39 aspirations performed on patients with suspected malignancy, 26 were diagnosed as positive (66.66%). Among other 13 non- neoplastic lesions only 6 were diagnosed positive under cytological examination by FNAC (46.15%). This could be due to more yield of material in malignant lesions than non-neoplastic lesions of liver and technical expertise of FNA In most of the cases Cytomorphological study of Hepatic masses by fine needle aspiration yields an accurate diagnosis but in some cases correlation with other investigations and ancillary studies are required for definitive diagnosis.

Umbilical cord plays pivotal role in development and well being of fetus. Any abnormality in the umbilical cord can affect the viability of the fetus. In spite of presence antenatal diagnostic modalities still fetal autopsy plays a vital role in identification and confirmation of the abnormalities which lead to intrauterine fetal death. To check for incidence of variety of cord abnormalities in perinatal fetal deaths. It is a retrospective observational study of 26 cases of perinatal deaths due to cord abnormalities taken from Jan 2013 to July 2021 in tertiary care center. In the study 26 cases of fetal autopsy were included over a period of nine years. Mean maternal age was 26 years. 12 cases (44.3%) were of vessel number defects. In which 11 were two vessel cords and the other was 5 vessel cord, 14 cases showed short cord. 8 cases showed normal cord length. 4 cases showed long cords. True knots were seen in one case. 3 cases (28%) were involving stenosed cords. and 5 cases (28.4%) were of supercoiling 3 twisted cords. Maternal co-morbidities were present in 3 cases.Umbilical cord anomaly is a major stress factor for fetus playing a key role in feto-maternal perfusion. Cord abnormalities can be clinically insignificant or can be severe leading to foetal death. The present study reemphasizes the importance of umbilical cord and its impact on wellbeing of foetus. Thus there is need to develop special and exclusive antenatal screening for umbilical cord abnormalities needs further research.