The gene products involved in mammalian mitochondrial DNA (mtDNA) maintenance and organization remain largely unknown. We report here a novel mitochondrial protein, Twinkle, with structural similarity to phage T7 gene 4 primase/helicase and other hexameric ring helicases. Twinkle colocalizes with mtDNA in mitochondrial nucleoids. Screening of the gene encoding Twinkle in individuals with autosomal dominant progressive external ophthalmoplegia (adPEO), associated with multiple mtDNA deletions, identified 11 different coding-region mutations co-segregating with the disorder in 12 adPEO pedigrees of various ethnic origins. The mutations cluster in a region of the protein proposed to be involved in subunit interactions. The function of Twinkle is inferred to be critical for lifetime maintenance of human mtDNA integrity.

The internal radial tire defects will affect the performance and the service life of the automobile. But the traditional detection method is to observe and detect in eyes using X-ray map which result that a lot of quality problems can not properly been judged out. This paper describes the X-ray image recognition using a fuzzy algorithm. The improved algorithm simplifies the traditional fuzzy algorithm complexity without the transform and inverse transform. The experimental results show that the improved algorithm makes the computational efficiency and extract more refined and clear edge for the radial tire which can correctly identify the failure and provide the necessary data processing.

Hu (2019) The current distribution of invasive mrigal carp (Cirrhinusmrigala) in Southern China, and its potential impacts on native mud carp (Cirrhinusmolitorella) populations,

It is known for rendering more torque in operation at low speed and suitably attaining high performance dynamic control for the inverter. This paper describes the research of ASR strategy for the spindle inverter control in CNC machine tool. The principles of the vector control and formulas for the coordinate transformation are illustrated. The accuracy of the torque depends on the accuracy of the motor parameters used in the control. So the powerful parameter tuning function should be enabled for all kinds of spindle to run effectively. The response of ASR will be perfect if the switching frequencies is used which is usually constant and set by the user.

During the drive speed operation with motor, due to the big difference between the synchronous speed and the motor speed, it likely causes too much current. When the current exceeds a certain limit, it will cause the drive to current protection of the acceleration. For the over-current drive in the tanker case, by analyzing the causes of over-current proceeding, the key points are described from the load check, the drive hardware check, the parameters check, input/output circuit inspection and so on. When the large start torque or acceleration torque is necessary, the motor torque of about 100 to 150% can be generated in the low frequency area by adjusting the torque boost.