Conductive cardiac patches have been proven to promote angiogenesis in infarcted myocardium; however, their conductive integrity, elasticity, and vascularization potential have not yet been optimized. The prevascularization of conductive elastic cardiac patches could be an effective strategy for building a substantial connection between the patch and the infarcted heart. Here, a coronary artery casting is introduced into a holey graphene oxide/polypyrrole‐incorporated polyhydroxyethyl methacrylate prefabricated gel to form a vascularized conductive elastic patch. The engineered patches are able to rebuild functional vascular anastomoses and provide strong electrical integration with infarcted hearts, resulting in effective myocardial infarction repair in vivo. RNA sequencing analyses further reveal that the conductive elastic patches under dynamic culture conditions upregulated cardiac muscle contraction‐ and ATP biosynthesis‐related mRNA expression in vitro. Together, this study demonstrates that the fabricated patches have versatile conductivity, elasticity, and vascularization properties, and could therefore be a promising candidate for heart repair.

Background: To evaluate the efficacy of transvaginal sonography (TVS) in the management of cesarean scar pregnancy (CSP). Methods: In this retrospective study conducted at Beijing Friendship Hospital of Capital Medical University, 142 CSP patients were collected from January 2015 to September 2019. Patients were divided into two groups, laparoscopy use group (Lap) and no laparoscopy use group (non-Lap) determined by the use of laparoscopy. The ultrasound parameters analyzed between these groups included maximal diameter of gestational sac, presence of fetal heartbeat, local myometrial thickness and grading of color Doppler signals. Results: The maximal diameter of gestational sac in the non-Lap and Lap groups was 2.330 ± 0.930 cm and 2.883 ± 0.420 cm respectively, p = 0.007. Local myometrial thickness was 0.25 (0.16) cm vs 0.16 (0.073) cm, p < 0.001. A positive fetal heartbeat and a grade III color Doppler signals were associated with the use of laparoscopy. Conclusions: TVS is beneficial for the effective treatment of women with CSP.