Background and aims: Cardiovascular disease is the main complication and cause of morbidity and mortality in type 2 diabetes mellitus (T2DM) patients. The main cause of complication in T2DM is oxidative stress caused by insulin resistance, hence it can increase lipid profiles (cholesterol, LDL, and triglycerides) which exacerbates endothelial dysfunction. Among various functional foods with antioxidant effects, probiotic foods have been reported to suppress oxidative stress, and also improve the fasting blood glucose (FBG) and lipid profile in patients with T2DM. The aim of this clinical trial is to study the effects of probiotics and conventional yogurt on FBG and lipid profile in patients with T2DM. Material and method: Thirty-eight patients with T2DM, aged 30 to 60 years old, were assigned to two groups in this randomized, doubleblind, controlled clinical trial. The subjects in the intervention group consumed 100 ml/day probiotic yogurt containing Lactobacillus acidophilus La-5 and Bifidobacterium lactis BB-12, whereas subjects in the control group consumed 100 ml/day conventional yogurt for four weeks. Anthropometric indices, dietary intake, physical activity, serum FBG, and lipid profile were evaluated at the beginning and end of the intervention. Results: Consumption of 100 mL/day conventional yogurt could significantly reduce the fasting blood glucose (FBG) level, whereas probiotic yogurt could not reduce FBG significantly. Although the total cholesterol and triglyceride were not improved after yogurt consumption, both type of yogurt could improve HDL-C level. Conclusion: Both conventional yogurt or probiotic yogurt could be used as functional food since it improved the HDL-C in type 2 DM patients.
This community service was carried out to improve the knowledge of Kutisari residents who identified had diabetes mellitus. The preliminary study was conducted regarding residents who identified with diabetes mellitus with deficiency of vitamin C and vitamin D intake. This community service program lasts for one year. The activity in this community service was collecting the data of respondents with diabetes mellitus, gave nutrition counselling, and directly provided food sources of vitamin C and vitamin D. Besides provided leaflets of vitamin C and vitamin D food sources, the nutrition counselling also measured the respondent’s blood sugar levels. Checking blood glucose levels was carried out to determine the glucose levels of residents who were identified as having diabetes mellitus. Intake of food sources of vitamin C and vitamin D was expected to lower blood glucose levels. The respondent received guava and chicken eggs as the food source of vitamin C and vitamin D. The purpose of this community service is to improve the respondent's knowledge about the food sources of vitamin C and vitamin D. Those foods will reduce the high blood glucose levels close to the normal values. The output of this community service activity is an online-published report.
Lactobacillus and Bifidobacterium are two genera of gram-positive bacteria that are widely used as probiotic products to improve the composition of the intestinal microbiota but until now the difference in the number of these bacteria in patients with type 2 diabetes mellitus and healthy people in Asia remains unclear. This study conducted a systematic review to analyze the differences in the number of Lactobacillus and Bifidobacterium bacteria in patients with type 2 diabetes and healthy people in Asia. The results showed that the number of Lactobacillus bacteria was higher in patients with type 2 diabetics than in healthy people. The number of Bifidobacterium bacteria in patients with type 2 diabetes tended to be lower than in healthy people, although there was some literature stating that there was no difference in the number of Bifidobacterium bacteria in patients with type 2 diabetes and in healthy people. Further research on the profile of Lactobacillus and Bifidobacterium bacteria per type (species) specifically in people with type 2 diabetes and healthy people of various ethnicities in Indonesia is needed to identify dysbiosis in people with type 2 diabetes and determine specific microbiota therapy for people with type 2 diabetes.
Latar belakang: Diabetes Mellitus tipe 2 merupakan penyakit yang disebabkan oleh penurunan sekresi insulin dan ditandai dengan peningkatan kadar glukosa darah (hiperglikemia). Vitamin D memiliki peranan terhadap sekresi insulin, metabolisme insulin dengan mempercepat perubahan proinsulin menjadi insulin dan meningkatkan sensitifitas insulin. Vitamin C adalah golongan mikronutrien yang memiliki peran penting dalam plasma manusia sebagai antioksidan. Vitamin C mempunyai sifat larut air dan mampu melawan radikal bebas. Fungsi Vitamin C adalah sebagai donor elektron atau agen pereduksi elektron sehingga mampu berperan sebagai antioksidan. Tujuan ingin mengetahui hubungan asupan bahan makanan sumber vitamin D dan vitamin C terhadap penurunan glukosa darah pada responden yang terindikasi Diabetes Mellitus tipe II. Metode penelitian pada penelitian ini adalah eksperimental dengan pendekatan crosssectional dengan menggunakan responden di wilayah kelurahan Kutisai, Surabaya. Dalam penelitian ini menggunakan 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Teknik pengambilan sampel yang digunakan adalah incidental sampling dengan jumlah 20 responden, yang terbagi menjadi 2 kelompok. Setiap kelompok 10 responden kelompok kontrol dan 10 responden kelompok perlakuan. Pengumpulan sampel dengan dilakukan dengan pengambilan darah hari 1 dan hari 7, wawancara FFQ–SQ. Hasil penelitian menunjukkan kedua kelompok baik kelompok kontrol dan perlakuan sama sama memiliki hasil tidak terdapat hubungan asupan bahan makanan sumber vitamin D dan vitamin C pada responden yang terindikasi diabetes mellitus tipe II . Kesimpulan Tidak ada hubungan antara asupan bahan makanan sumber vitamin D dan vitamin C terhadap penurunan kadar glukosa darah pada responden yang terindikasi Diabetes Mellitus tipe IIKata kunci : Diabetes Mellitus Glukosa, Vitamin C, Vitamin D
Desember 2019, penyakit coronavirus 2019 (Covid-19) yang disebabkan oleh (SARS-CoV-2) pecah di Wuhan, China. Indonesia melaporkan kasus pertama pada 2 Maret 2020. Kasus meningkat dengan cepat di seluruh wilayah Indonesia. Vaksinasi Covid-19 adalah bagian dari upaya penanganan pandemi Covid-19 yang menyeluruh dan terpadu, beriringan dengan disiplin penerapan protokol kesehatan 3M dan pelaksanaan 3 T. Hasil survei penerimaan vaksin covid 19 oleh Kementerian Kesehatan, ITAGI (Indonesian Technical Advisory Group on Immunization), UNICEF dan WHO pada September 2020 menunjukkan bahwa sebagian besar masyarakat (74 persen) sudah mengetahui rencana pemerintah untuk melaksanakan vaksinasi Covid-19. Sebanyak 65 persen bersedia divaksinasi, sekitar 27 persen masih ragu. Dan hanya sebagian kecil atau sekitar 8 persen yang menyatakan menolak dengan alasan khawatir akan keamanan, efektivitas dan kehalalan vaksin. Hasil survey menunjukkan bahwa mereka yang memiliki informasi tentang vaksinasi cenderung lebih menerima vaksinasi Covid-19. Hal ini menunjukkan pentingnya memastikan masyarakat mendapatkan informasi yang akurat tentang vaksinasi Covid-19. Oleh karena itu, kegiatan pengabdian masyarakat ini penting diberikan kepada masyarakat dalam bentuk penyuluhan dan sosialisasi tentang Vaksin Covid-19. Kegiatan Pengabdian Masyarakat ini dikemas dalam bentuk webinar. Webinar ini menghadirkan sejumlah narasumber antara lain Gubernur Jawa Timur dan Ketua Umum PP Muslimat NU, Kepala Dinas Kesehatan Provinsi Jawa Timur, Dosen Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Brawijaya dan Ketua Satgas NU Peduli Covid-19 Malang Raya), serta Dosen Prodi Keperawatan Fakultas Kedokteran UNUSA dan Pengurus Wilayah Muslimat NU Jawa Timur. Dari hasil kegiatan pengabdian masyarakat diharapakan pengurus Muslimat NU mengerti dan memahami mengenai informasi yang akurat tentang vaksinasi Covid-19. Muslimat NU juga dapat berkontribusi menyukseskan program vaksinasi yang dilaksanakan oleh pemerintah.
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