Music with exercise could improve left ventricular performance, thereby decreasing the extent of tissue damage in the left ventricle of the heart. The study aimed to measure sports intervention with fast tempo music (Allegro) on the extent of cellular damage to the left ventricular myocardial tissue of the heart. This study used an experimental research design using a Random Controlled Group Posttest-Only Design. A control group was played Allegro music, a moderate sports group was played Allegro music, and a highintensity sports group was played Allegro music using Wistar white rats of the male sex. Sport was performed using a special treadmill for mice for ten weeks. Data analysis was performed using ANOVA test. The results of this study show that there was a difference in left ventricular wall thickness in the heart between the control group and allegro music group, moderate exercise group with allegro music, and highintensity group with allegro music (F=19,636; p=0.001). This study showed that high-intensity exercise with allegro music has the potential to improve the health of the left ventricle of the heart.
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