Objectives: The present study was carried out to compare a bilingual (Balouchi & Persian) vocal patient education program and routine education on patient's self-efficacy in type 2 diabetes patients suffering from visual impairments. Materials and methods:This semi-experimental study was conducted on patients with type 2 diabetes mellitus (T2DM) suffering from visual impairments. A total number of 90 participants were divided into two equal groups: 45 patients in the intervention group and 45 controls in the routine care group. A permuted block randomization (AB) using a random number generator by default was implemented to organize the two groups. One of the researchers collected the demographics and self-efficacy data through face to face interviews. The diabetes management self-efficacy scale (DMSES) was used for self-efficacy assessment. Patients in the intervention group received an MP3 Player including 90 minutes of vocal education.Results: There were no significant differences in participants' demographic characteristics between the two study groups. However, a remarkable rise was observed in the self-efficacy score (P<0.0001) as well as HA 1C and FBS levels among patients in the intervention group after vocal education (P<0.001).Conclusions: The findings of the present research suggest nursing and public health policy makers to reconsider their traditional patient education programs, particularly for diabetes patients with visual impairments among indigenous people.