Several fundamental research and applications in biomedicine and microfluidics often require controlled manipulation of suspended micro- and nanoscale particles. Speckle tweezers (ST) by incorporating randomly distributed light fields have been used to control micro-particles with refractive indices higher than their medium and to perform manipulation tasks such as guiding and sorting. Indeed, compared to periodic potentials, ST represents a wider possibility to be operated for such tasks. Here, we extend the usefulness of ST into micro-particles of low index with respect to the surrounding. Repelling of such particles by high intensity regions into lower intensity regions makes them to be locally confined, and the confinement can be tuned by changing the average grain intensity and size of the speckle patterns. Experiments on polystyrenes and liposomes validate the procedure. Moreover, we show that ST can also manipulate the nano-particle (NP)-loaded liposomes. Interestingly, the different interactions of NP-loaded and empty liposomes with ST enable collective manipulation of their mixture using the same speckle pattern, which may be explained by inclusion of the photophoretic forces on NPs. Our results on the different behaviors between empty and non-empty vesicles may open a new window on controlling collective transportation of drug micro-containers along with its wide applications in soft matter.

In this paper, we construct the generalized parton distribution (GPD) in terms of the kinematical variables [Formula: see text], [Formula: see text], [Formula: see text], using the double distribution model. By employing these functions, we could extract some quantities which makes it possible to gain a three-dimensional insight into the nucleon structure function at the parton level. The main objective of GPDs is to combine and generalize the concepts of ordinary parton distributions and form factors. They also provide an exclusive framework to describe the nucleons in terms of quarks and gluons. Here, we first calculate, in the Double Distribution model, the GPD based on the usual parton distributions arising from the GRV and CTEQ phenomenological models. Obtaining quarks and gluons angular momenta from the GPD, we would be able to calculate the scattering observables which are related to spin asymmetries of the produced quarkonium. These quantities are represented by [Formula: see text] and [Formula: see text]. We also calculate the Pauli and Dirac form factors in deeply virtual Compton scattering. Finally, in order to compare our results with the existing experimental data, we use the difference of the polarized cross-section for an initial longitudinal leptonic beam and unpolarized target particles [Formula: see text]. In all cases, our obtained results are in good agreement with the available experimental data.