Women with tubal ectopic pregnancies have high levels of circulating interleukin 6 (IL-6). IL-6 treatment in vitro significantly reduces the ciliary activity of tubal epithelium. The effects of IL-6 on target cells occur via the formation of a high-affinity complex with its receptors IL-6Rα and glycoprotein 130 (Gp130). IL-6Rα is specifically expressed in the cilia of the epithelial cells. In this study, we performed a quantitative reverse transcriptase polymerase chain reaction to determine the mRNA expression of IL-6Rα and Gp130 in the fallopian tubes obtained from 12 women with ectopic pregnancies, 12 women with normal pregnancies, and 12 healthy nonpregnant women in the luteal phase of their menstrual cycle. Fallopian tubes were evaluated from specimens taken during tubal ligation in normal pregnancies and nonpregnant fertile women or during tubal surgery in ectopic pregnancies. We observed that IL-6Rα mRNA expression in fallopian tubes was increased in ectopic pregnancy compared with that in the midluteal phase. We also found that the Gp130 mRNA expression was significantly lower in fallopian tubes from ectopic pregnancies than in those from nonpregnant women during the midluteal phase of their menstrual cycle, although its expression was noticeably high in fallopian tubes in the midluteal phase, which suggests that high Gp130 levels may possibly contribute to embryo transport into the uterus.

No abstract

Anthropometry of neurocranium as well as intelligence has been reported to have a bidirectional effects. The aim of the present investigation is to study the relationship between neurocranium anthropometry and Intelligence Quality (IQ) in students living in tropical and cold areas in Iran. Materials and Methods: The method of the present investigation is comparative and analytical descriptive. A total number of 100 healthy Azari medical students were included. The neurocranium length, width, and height were measured by Martin Saller caliper. The students' brain capacity was determined using Lee Pearson formula. In the next phase, all students were tested with Wechsler intelligence test. MRI was performed in 10 students with the highest IQ as well as in 10 students with the lowest IQ. The relationship between frontal and temporal lobes mass with full-scale intelligence quotient (FSQI) was evaluated. Results: The results indicated that a higher brain capacity was accompanied by the highest IQ. The significant differences were observed among male and female students from cold and tropical areas. A higher FSIQ rate in male students was accompanied by larger mass of the frontal lobe. The highest IQ was observed in female students with a larger mass of the temporal lobe. FSIQ was correlated to the mass of the frontal lobe and the temporal lobe in male and female students, respectively. Conclusion: This study revealed a relationship between weather, brain volume, and the mass of the frontal and temporal lobes with FSIQ.